Indirect and direct costs of treating patients with ankylosing spondylitis in the Brazilian public health system

Azevedo, Valderílio Feijó; Rossetto, C.N.; Lorencetti, Pedro G.; Tramontin, Mariana Y.; Fornazari, Bruna; Araújo, Denizar Vianna

doi:10.1016/j.rbre.2015.08.009

Cited by 3 publications

(2 citation statements)

References 18 publications

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“…It is clear, however, that indirect costs are those employed when there is loss of functionality and productivity resulting from health problems, 18 such as sick leave, social security admission, pensions, among others. [19][20] In this study, there were costs with treatment of AKF greater than R$ 37.6 million to public coffers, and Bahia stood out with the highest burden, totaling R$ 12,097,684.22 (32.1%), according to Table 2. It is noteworthy that during hospitalization, the user goes through various sectors responsible for contributing to their recovery, demanding different costs for each procedure performed.…”

Section: Discussionmentioning

confidence: 96%

Insuficiência renal aguda no Nordeste brasileiro: morbimortalidade e custos públicos

Júnior

Cruz

Nunes

et al. 2019

Rev enferm UFPE on line.

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Objetivo: descrever a morbimortalidade hospitalar e custos públicos relacionados à insuficiência renal aguda no Nordeste brasileiro. Método: trata-se de estudo quantitativo, ecológico e descritivo realizado com dados do Sistema de Informações Hospitalares. Coletaram-se as variáveis: internações; óbitos; mortalidade; valores dos serviços hospitalares; valores médios gastos com as internações e média de permanência hospitalar. Analisaram-se os dados com estatística descritiva, apresentando-os em tabelas elaboradas pelo software Excel. Resultados: registraram-se 21.100 internações, 4.460 óbitos e mortalidade de 21,1%. Destacaram-se a Bahia nas internações (28,6%) e óbitos (28,7%) e Sergipe na letalidade (35,6%). Gerou-se custo público superior a R$ 37,6 milhões e a Bahia responsabilizou-se por 32,1%. Revelou-se valor médio de R$ 1.969,97 para cada internação e a média de permanência hospitalar foi de 10,2 dias. Conclusão: conclui-se que as variáveis epidemiológicas apresentaram maior prevalência nos Estados da Bahia e Sergipe. Evidenciou-se, além disso, comportamento crescente das internações, implicando o incremento dos custos públicos. Descritores: Saúde Pública; Nefrologia; Nefropatias; Epidemiologia; Custos de Cuidados de Saúde; Sistemas de Informação. Abstract Objective: to describe hospital morbidity and mortality and public costs related to acute renal failure in northeastern Brazil. Method: this is a quantitative, ecological and descriptive study conducted with data from the Hospital Information System. The following variables were collected: hospitalizations; deaths; mortality; values of hospital services; average values spent on hospitalizations and average hospital stay. Data was analyzed with descriptive statistics and presented in tables prepared by Excel software. Results: 21,100 hospitalizations, 4,460 deaths and 21.1% mortality were registered. Bahia stood out in hospitalizations (28.6%) and deaths (28.7%) and Sergipe in lethality (35.6%). It generated a public cost over R $ 37.6 million and Bahia accounted for 32.1%. An average value of R $ 1,969.97 was revealed for each hospitalization and the average hospital stay was 10.2 days. Conclusion: it is concluded that the epidemiological variables were more prevalent in the states of Bahia and Sergipe. In addition, the increasing behavior of hospitalizations was evidenced, implying an increase in public costs. Descriptors: Public Health; Nephrology; Kidney Diseases; Epidemiology; Health Care Costs; Information Systems.Resumen Objetivo: describir la morbimortalidad hospitalaria y los costos públicos relacionados con la Insuficiencia Renal Aguda en el Noreste de Brasil. Método: se trata de un estudio cuantitativo, ecológico y descriptivo realizado con datos del Sistema de Informaciones Hospitalarias. Se recogieron las siguientes variables: hospitalizaciones; muertes, mortalidad, valores de los servicios hospitalarios; promedio de valores gastados en admisiones y promedio de permanencia hospitalaria. Los datos se analizaron con estadísticas descriptivas y se presentaron en tablas elaboradas por el software Excel. Resultados: se registraron 21.100 admisiones, 4.460 muertes y 21.1% de mortalidad. Bahía se destacó en hospitalizaciones (28.6%) y muertes (28.7%), y Sergipe en letalidad (35.6%). Se generó un costo público de más de R$ 37,6 millones y Bahía fue responsable del 32.1%. El valor medio de R $ 1,969.97 se reveló para cada hospitalización y la permanencia hospitalaria con promedio de 10,2 días. Conclusión: se concluye que las variables epidemiológicas presentaron mayor prevalencia en los Estados de Bahía y Sergipe. Además, hubo evidencia de un mayor comportamiento de hospitalización, lo que implica un aumento en los costos públicos. Descriptores: Salud Pública; Nefrología; Enfermedades Renales; Epidemiología; Costos de la Atención en Salud; Sistemas de Información.

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Section: Discussionmentioning

confidence: 96%

Insuficiência renal aguda no Nordeste brasileiro: morbimortalidade e custos públicos

Júnior

Cruz

Nunes

et al. 2019

Rev enferm UFPE on line.

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“…Many comorbidities, chronic pain, functional disabilities, and resource consumption are associated with ankylosing spondylitis. Thus, the management of AS may result in high direct and indirect costs to the patients and the healthcare system [ 6 , 7 ]. AS has a mostly idiopathic aetiology.…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of Physiotherapy in Patients with Ankylosing Spondylitis: A Systematic Review and Meta-Analysis

et al. 2022

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This study aimed to evaluate the safety and effectiveness of non-pharmacological interventions supervised by a physiotherapist in patients with Ankylosing Spondylitis, PROSPERO Protocol number CRD42020209453. Five databases (PubMed, PEDro, Scopus, Web of Science Core, and EMBASE) and reference lists with relevant articles were searched. Randomised controlled trials (RCTs) on the effectiveness of non-pharmacological interventions supervised by a physiotherapist were compared with usual care or home-based exercise programmes. Two investigators independently screened eligible studies. A total of 12 RCTs satisfied eligible criteria. The risk of bias ranged between medium and high. The meta-analysis results indicated that between supervised physiotherapy and usual care, the former was significantly associated with improvement in disease activity (standardised mean difference = −0.37, 95% CI, −0.64; −0.11; p < 0.001, I2 = 71.25%, n = 629), and functional capacity (standardised mean difference = −0.36, 95% CI, −0.61; −0.12, p < 0.05; n = 629). No statistically significant differences emerged when interventions were compared with home-based exercise programmes. Supervised physiotherapy is more effective than usual care in improving disease activity, functional capacity, and pain in patients with ankylosing spondylitis. No significant improvements emerged when supervised physiotherapy and home-based exercise programmes were compared. Further investigation and RCTs with larger samples are needed.

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Costs of Drug Therapy in Patients with Ankylosing Spondylitis in Brazil

et al. 2016

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IntroductionThe Brazilian Public Health System offers free-of-charge drug treatment for ankylosing spondylitis (AS) to all Brazilian citizens. We report here the first population-based cohort study on patients with AS in Brazil. The aim of this study was to evaluate the costs of the tumour necrosis factor (anti-TNF) blockers and disease-modifying antirheumatic drugs (DMARDs) that were used in the treatments of patients with AS in Brazil between March 2010 and September 2013.MethodsA retrospective cohort study was performed using administrative databases. All patients with a diagnosis of AS who were aged 18 years or older and had been dispensed anti-TNF or DMARDs were included in the analysis. The cost analysis was carried out from the health system perspective, and the results were described as median monthly cost per capita and the annual cost over the study period.ResultsA search of the databases identified 1251 patients with AS who were treated during the study period, of whom 63.3% were male; the median age was 41 years. During the study period, 78.0% of patients initiated treatment with anti-TNF drugs and 22.0% with DMARDs. The median monthly cost per capita was US$ 1650 for anti-TNF therapy and US$ 25 for treatment with DMARDs. Among the anti-TNF drugs, therapy with etanercept was associated with the lowest cost per patient, followed by adalimumab and infliximab. No difference in monthly cost was observed in relation to gender and age.ConclusionThe cost per patient of treating AS in this study cohort was lower with etanercept than with adalimumab and infliximab. These results highlights the economic burden of treating patients with AS.

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Indirect and direct costs of treating patients with ankylosing spondylitis in the Brazilian public health system

Cited by 3 publications

References 18 publications

Insuficiência renal aguda no Nordeste brasileiro: morbimortalidade e custos públicos

Insuficiência renal aguda no Nordeste brasileiro: morbimortalidade e custos públicos

Effectiveness of Physiotherapy in Patients with Ankylosing Spondylitis: A Systematic Review and Meta-Analysis

Costs of Drug Therapy in Patients with Ankylosing Spondylitis in Brazil

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