O efeito do plasma rico em plaquetas no reparo de lesões musculares em ratos

Quarteiro, Marcelo Luiz; Tognini, João Ricardo F.; Oliveira, Everton Lucas Flores de; Silveira, Izabelli

doi:10.1016/j.rbo.2014.09.002

Cited by 10 publications

(2 citation statements)

References 24 publications

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“…The results observed in the present case series corroborate the findings of both experimental and clinical studies that demonstrate the effects of intralesional injection of PRP on muscle injuries. Overall, these previous studies reported better muscle regeneration, increased neovascularization, and reduced fibrosis (Wright-Carpenter et al, 2004;Hammond et al, 2009;Gigante et al, 2012;Quarteiro et al, 2015).…”

Section: Discussionmentioning

confidence: 83%

“…These two actions may explain the absence of pain after 30 days of treatment and may have been enhanced by therapeutic ultrasound sessions performed on alternate days during the treatment period. Quarteiro et al (2015) highlighted that the concentrations of different growth factors in PRP obtained from different species (rats, rabbits, sheep, horses, and humans) show significant variation, which directly influences the results obtained in both experimental studies and clinical trials. Therefore, studies on standardized protocols are needed to increase knowledge about the effects of PRP used on the treatment of back pain in horses.…”

Section: Discussionmentioning

confidence: 99%

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Multimodal therapy for treatment of equine back pain: a report of 15 cases

Melo

Ferreira²

2021

Braz. J. Vet. Med.

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Back pain and diseases of the spine are considered significant problems in equine sports and veterinary medicine. This article reports a multimodal approach to the treatment of equine back pain using ozonized platelet rich plasma (PRP), dynamic mobilization exercises, and therapeutic shoeing in 15 horses involved in the vaquejada discipline. Fifteen American Quarter Horses of both sexes engaged in vaquejada in the state of Rio Grande do Norte, Brazil, with a mean age of 8.61 ± 1.73 years were examined at a training center for lower performance diagnostics or back pain. A complete clinical examination was performed on all horses at rest to determine the general conformation and alterations in posture, symmetry, and curvature of the spine. The horses were examined while walking and trotting in straight lines and circles to determine the presence of lameness and/or gait asymmetry. Spinal abnormalities on clinical examination were classified on a scale of 0 to 5 based on the following parameters: degree of response to pain from back palpation, hypertonicity of the back muscles, stiffness of the thoracolumbar joint, and physical dysfunction. After physical examination, ultrasound was performed to identify the cause of the thoracolumbar pain. The therapeutic protocol consisted of the intralesional application of ozonized PRP combined with therapeutic ultrasound, dynamic mobilization exercises, and therapeutic shoeing. All treated animals returned to sports activities at a higher level of performance than at the beginning of the treatment. Six months after treatment, telephone contact was made with the owner or trainer to determine if the back pain had relapsed. None of the animals relapsed during this period, and they participated in vaquejada normally.

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Section: Discussionmentioning

confidence: 83%

Section: Discussionmentioning

confidence: 99%