Neonatal COVID-19: little evidence and the need for more information

Procianoy, Renato S.; Silveira, Rita de Cássia dos Santos; Manzoni, Paolo; Sant’Anna, Guilherme M.

doi:10.1016/j.jped.2020.04.002

Cited by 20 publications

(24 citation statements)

References 17 publications

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“…Por meio dos estudos analisados, percebe-se que alguns casos de COVID-19 positivos, foram relatados no Brasil por meio do noticiário ou de apresentações clínicas (Procianoy, et al, 2020), o que reforça que a vigilância deve ser mantida nesta população.…”

Section: Discussionunclassified

Práticas do cuidado com recém-nascido em tempos de pandemia: revisão integrativa

Costa

Barbosa

Rezende

et al. 2021

RSD

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O objetivo deste estudo foi identificar evidências científicas sobre boas práticas no cuidado ao recém-nascido, da sala de parto ao domicílio, em tempos de COVID-19. Trata-se de uma revisão Integrativa. Assim, o delineamento desse estudo surgiu a partir da seguinte questão de pesquisa: o que se sabe até o momento da literatura científica sobre as práticas do cuidado ao recém-nascido, em tempos de pandemia? Após percorrer as etapas metodológicas foi possível identificar 05 artigos, todas as publicações são datadas no ano 2020 e focadas na prevenção e os cuidados prestados aos recém-nascidos. Diante da analise da literatura disponível, evidenciou-se diversas divergências sobre a implementação das praticas de cuidado. Visto isso, torna-se viável a criação de um protocolo de assistência aos recém-nascidos em tempos de pandemia de COVID-19, a fim de estabelecer um padrão de qualidade. Ainda sim, é preciso a maior realização de pesquisas referentes à assistência aos recém-nascidos considerando o período de pandemia do COVID-19, em especial de autores brasileiros.

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Section: Discussionunclassified

Práticas do cuidado com recém-nascido em tempos de pandemia: revisão integrativa

Costa

Barbosa

Rezende

et al. 2021

RSD

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“…Hence, it is advisable to use the appropriate size filter for newborn infants and avoid prolonged ventilation using this approach, especially in the smaller, extremely preterm infants. 12,13 It is also unclear if the addition of a filter could affect ventilatory technique especially during mask ventilation. The extra weight of the filter may impair effective mask ventilation technique leading to increased leak.…”

Section: Particle Filtermentioning

confidence: 99%

“…There is insufficient evidence behind the airflow dispersion pattern and transmission risk to HCWs when performing AGMPs during neonatal resuscitation or stabilization. 12,13 It is postulated that aerosolization during AGMPs in neonatal resuscitation is much lower than that of an adult due to the lower tidal volumes with dispersion distances of <2 cm estimated. 6,12 However, there are no neonatal data to support this and it is difficult to extrapolate the limited adult data 14 into neonatal settings.…”

Section: Introductionmentioning

confidence: 99%

Airflow dispersion during common neonatal resuscitation procedures: A simulation study

Kwok

Swaby

Sharkey

2021

Pediatric Pulmonology

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Background: Aerosol generating medical procedures (AGMPs) are common during newborn resuscitation. Neonates with respiratory viruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may pose a risk to healthcare workers. International guidelines differ on methods to minimize the risk due to limited data.Objective: We examined the expiratory airflow dispersion during common neonatal resuscitation AGMPs using infant simulators.Methods: Expiratory airflow dispersion in term and preterm manikins was simulated (n = 288) using fine particle smoke at tidal volumes of 5 ml/kg. Using ImageJ, we quantified dispersion during common airway procedures including endotracheal tube (ETT) and T-piece ventilation.Results: Maximal expiratory dispersion distances for the unsupported airway and disconnected uncuffed ETT scenarios were 30.2 and 22.7 cm (term); 22.1 and 17.2 cm (preterm), respectively. Applying T-piece positive end expiratory pressure (PEEP) via an ETT (ETT PEEP ) generated no expiratory dispersion but increased tube leak during term simulation, while ventilation breaths (ETT VENT ) caused significant expiratory dispersion and leak. There was no measurable dispersion during face mask ventilation. For term uncuffed ETT ventilation, the particle filter eliminated expiratory dispersion but increased leak. No expiratory dispersion and negligible leak were observed when combining a cuffed ETT and filter. Angulated T-pieces generated the greatest median dispersion distances of 35.8 cm (ETT PEEP ) and cm (ETT VENT ).Conclusions: Airflow dispersion during neonatal AGMPs is greater than previously postulated and potentially could contaminate healthcare providers during resuscitation of infants infected with contagious viruses such as SARS-CoV-2. It is possible to mitigate this risk using particle filters and cuffed ETTs. Applicability in the clinical setting requires further evaluation.

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“…In a digital study of a baby born to a mother with COVID-19, 2 hours after birth, the baby's antibodies and cytokines levels were abnormal. Given that IgM antibodies were not transmitted to the fetus through the placenta, the IgM levels indicated that the baby was infected in the womb [22,23] .…”

Section: Vertical Transmission Of Covid-19 Virus From Pregnant Mother To Infantmentioning

confidence: 99%

Management of a Pregnant Woman during the Pandemic of COVID-19: A Review

Nabizadeh

Ravanshad

Ahmadi

et al. 2021

IEM

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Background: In late December 2019, a new coronavirus called SARS-CoV-2, as the causative agent of COVID-19 (coronavirus disease 2019) pneumonia, began to spread from Wuhan, China. The SARS-CoV-2 virus is currently threatening the world's public health and so far, no specific and effective treatment has been found for the disease. Due to the physiological changes in the body of pregnant women during pregnancy, the occurrence of infection in pregnant women could affect the health of both mother and her fetus. The present paper aimed to study the findings related to the effects of coronavirus on pregnant women and their fetuses during pregnancy, diagnostic methods, care protocols in pregnant women, and postpartum care. Methods: The information included in this review was extracted from articles, published protocols, and valid statistics. In this study, articles indexed in Latin databases (PubMed, Google Scholar, Science Direct, Embase, Scopus), clinical protocols, and reports of reputable health organizations from January to august 2020 were reviewed using a combination of the following keywords: COVID-19, SARS-CoV-2, pregnant woman, and pregnancy. Conclusion: Due to the global prevalence of this virus, protocols and health care should be applied for pregnant women in accordance with other people. It is also necessary to take preventive measures at the community level. In this regard, the management of pregnant women with COVID-19 infection is of particular importance during the pandemic period of the disease. However, more extensive studies are required to validate these principles. This review summarized the precautions that should be taken before and after delivery.

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Neonatal COVID-19: little evidence and the need for more information

Cited by 20 publications

References 17 publications

Práticas do cuidado com recém-nascido em tempos de pandemia: revisão integrativa

Práticas do cuidado com recém-nascido em tempos de pandemia: revisão integrativa

Airflow dispersion during common neonatal resuscitation procedures: A simulation study

Management of a Pregnant Woman during the Pandemic of COVID-19: A Review

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