Neonatal and pediatric extracorporeal membrane oxygenation in developing Latin American countries

Kattan, Javier; González, Álvaro; Castillo, Andrés; Canêo, Luiz Fernando

doi:10.1016/j.jped.2016.10.004

Cited by 13 publications

(8 citation statements)

References 35 publications

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“…The mortality rate was slightly decreased but no significant difference in two period due to the very low number of ECMO patients in pre-ECMO committee program period. The ECMO survival rate and survival rate to discharge were 70 and 50%, respectively, which were comparable to the previous studies ( 12 , 13 , 16 , 17 ). This study found the ECMO survival rate to discharge in VA and VV were 50%, while the ELSO registry summarized that the mortality rate of VA ECMO was 51.9% and VV ECMO was 61.8% in Asia pacific registration ( 18 ).…”

Section: Discussionsupporting

confidence: 89%

“…Additionally, patients with AKI were shown to require a longer duration of ECMO support, longer ventilator days, and had a higher mortality rate (17,21,22). A recent meta-analysis study in 3,523 pediatric patients on ECMO demonstrated that AKI was significantly associated with reduced survival outcome (23).…”

Section: Discussionmentioning

confidence: 99%

“…The incidences of AKI in neonatal and pediatric ECMO patients were estimated to be between 50 and 62% in a multicenter retrospective observational cohort study ( 21 ). Additionally, patients with AKI were shown to require a longer duration of ECMO support, longer ventilator days, and had a higher mortality rate ( 17 , 21 , 22 ). A recent meta-analysis study in 3,523 pediatric patients on ECMO demonstrated that AKI was significantly associated with reduced survival outcome ( 23 ).…”

Section: Discussionmentioning

confidence: 99%

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Clinical Characteristics and Outcomes of Children With Extracorporeal Membrane Oxygenation in a Developing Country: An 11-Year Single-Center Experience

et al. 2021

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Introduction: Extracorporeal Membrane Oxygenation (ECMO) is a lifesaving procedure for patients with refractory cardiac or respiratory failure. The indications for ECMO are growing, and it is increasingly being used to support cardiopulmonary failure in children. However, the risks and benefits of ECMO should be weighed before deploying it on the patients. The objectives of this study were to identify the mortality risk factors and to determine the ECMO outcomes.Methods: The retrospective chart reviews were done for all patients aged 1 day−20 years old receiving ECMO between January 2010 and December 2020.Results: Seventy patients were enrolled in the study. The median age was 31.3 months. The incidence of VA and VV ECMO was 85.7 and 14.3%, respectively. The most common indication for ECMO was the failure to wean off cardiopulmonary bypass after cardiac surgery. Pre-existing acute kidney injury (OR 4.23; 95% CI 1.34–13.32, p = 0.014) and delayed enteral feeding (OR 3.85, 95% CI 1.23–12.02, p = 0.020), and coagulopathy (OD 12.64; 95% CI 1.13–141.13, p = 0.039) were associated with the higher rate of mortality. The rates of ECMO survival and survival to discharge were 70 and 50%, respectively.Conclusion: ECMO is the lifesaving tool for critically ill pediatric patients. Pre-existing acute kidney injury, delayed enteral feeding, and coagulopathy were the potential risk factors associated with poor outcomes in children receiving ECMO. However, ECMO setup can be done successfully in a developing country.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Clinical Characteristics and Outcomes of Children With Extracorporeal Membrane Oxygenation in a Developing Country: An 11-Year Single-Center Experience

et al. 2021

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“…Nos últimos anos, vários biomarcadores da HP foram investigados com o intuito de buscar um método eficiente e não invasivo de estratificação e monitorização (PLÁCIDO et al, 2017). Nos anos 1970, a oxigenação por membrana extracorpórea foi usada para administrar a insuficiência respiratória e a hipertensão pulmonar e, de certa forma, posteriormente para assistência cardíaca ventricular (KATTAN et al, 2017).…”

Section: Discussionunclassified

Cuidado De Enfermagem Na Atenção Primária À Criança Com Síndrome De Williams-Beuren: Uma Revisão Integrativa

Nonato¹,

Klodzinski²,

Nadalin³

et al. 2020

Destaques Acadêmicos

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O presente artigo trata-se de uma revisão integrativa tendo como objetivos conhecer a fisiopatologia da síndrome de Williams-Beuren e suas consequências no atraso psicomotor da criança e elaborar um plano de cuidados com base nos diagnósticos reais e potenciais elencados baseando-se na taxonomia NANDA 2018-2020, a partir da emergência do tema numa realidade de atenção primária de Curitiba, vivenciada por acadêmicas de enfermagem, por meio da metodologia da problematização, utilizando o Arco de Maguerez, aplicado a um caso fictício. Para a teorização, realizada busca em base de dados, sendo eleitas BVS, Pubmed e Scielo, resultando no total de 27 artigos. A partir do esclarecimento da complexidade cromossômica envolvida na síndrome e as complicações decorrentes da expressividade dessa alteração, compreende-se que a atuação de enfermagem na atenção primária frente à Síndrome de Williams-Beuren aborda integralmente a criança desde seu nascimento e contínuo acompanhamento do desenvolvimento ao longo da vida, pois por meio da monitorização, faz-se possível a prevenção, identificação e intervenção diante das complicações inerentes à síndrome.

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“…2 Since the 1970s, ECMO has been used as a therapeutic alternative at most tertiary-care hospitals in the United States and Europe; however, in Mexico its use was not established until 2013. 3 In Latin American countries, some investigation has been conducted in which the use of this procedure is reported, but with a high mortality rate. 4 After 2013, the pediatric ECMO program was initiated at the Pediatric Intensive Care Unit of Christus Muguerza High Specialty Hospital in Monterrey, Nuevo Leon, Mexico.…”

Section: Introductionmentioning

confidence: 99%

Venoarterial extracorporeal membrane oxygenation in heart surgery post-operative pediatric patients: A retrospective study at Christus Muguerza Hospital, Monterrey, Mexico

Vargas-Camacho¹,

Contreras-Cepeda²,

Gómez-Gutiérrez³

et al. 2020

SAGE Open Medicine

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Objectives: Extracorporeal membrane oxygenation is a life support procedure developed to offer cardiorespiratory support when conventional therapies have failed. The purpose of this study is to describe the findings during the first years using venoarterial extracorporeal membrane oxygenation in pediatric patients after cardiovascular surgery at Christus Muguerza High Specialty Hospital in Monterrey, Mexico. Methods: This is a retrospective, observational, and descriptive study. The files of congenital heart surgery post-operative pediatric patients, who were treated with venoarterial extracorporeal membrane oxygenation from January 2013 to December 2015, were reviewed. Results: A total of 11 patients were reviewed, of which 7 (63.8%) were neonates and 4 (36.7%) were in pediatric age. The most common diagnoses were transposition of great vessels, pulmonary stenosis, and tetralogy of Fallot. Survival rate was 54.5% and average life span was 6.3 days; the main complications were sepsis (36.3%), acute renal failure (36.3%), and severe cerebral hemorrhage (9.1%). The main causes of death were multi-organ dysfunction syndrome (27.3%) and cerebral hemorrhage (18.2%). Conclusion: The mortality rates found are very similar to those found in a meta-analysis report published in 2013 and the main complication and causes of death are also very similar to the majority of extracorporeal membrane oxygenation reports for these kinds of patients. Although the results are encouraging, early sepsis detection, prevention of cerebral hemorrhage, and renal function monitoring must be improved.

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Neonatal and pediatric extracorporeal membrane oxygenation in developing Latin American countries

Cited by 13 publications

References 35 publications

Clinical Characteristics and Outcomes of Children With Extracorporeal Membrane Oxygenation in a Developing Country: An 11-Year Single-Center Experience

Clinical Characteristics and Outcomes of Children With Extracorporeal Membrane Oxygenation in a Developing Country: An 11-Year Single-Center Experience

Cuidado De Enfermagem Na Atenção Primária À Criança Com Síndrome De Williams-Beuren: Uma Revisão Integrativa

Venoarterial extracorporeal membrane oxygenation in heart surgery post-operative pediatric patients: A retrospective study at Christus Muguerza Hospital, Monterrey, Mexico

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