Serum phenylalanine in preterm newborns fed different diets of human milk

Thomaz, Débora Marchetti Chaves; Serafin, Paula O.; Palhares, Durval Batista; Tavares, Luciana Venhofen Martinelli; Grance, Thayana R.S.

doi:10.1016/j.jped.2014.02.003

Cited by 7 publications

(1 citation statement)

References 18 publications

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“…A study conducted with 24 PTNBs divided into three groups fed with HM provided by HMBs supplemented with 5% of bovine-based protein, vaporized HM, and lyophilized HM, respectively, observed that despite the lack of negative metabolic repercussions while the study was being carried out, the PTNBs fed with HM supplemented with bovine-based protein may exhibit damaged future cognitive development since the additive increases blood phenylalanine content of the neonates (Thomaz et al, 2014).…”

Section: Reconstituted Human Milk Versus Infant Formulasmentioning

confidence: 99%

Availability of macronutrients in lyophilized human milk used to supply the nutritional needs of preterm newborns

Souza

Ponhozi

Manin

et al. 2022

RSD

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Human Milk (HM) is the optimal source of nutrition for preterm newborns (PTNBs). Still, adapting the appropriate nutrient supply for these babies is a major challenge. Lyophilization is a common procedure employed to conserve HM that enables reconstitution of the milk in different volumes, therefore it provides better control of nutrient content, and consequently facilitates adapting its nutritional content to better fulfill the needs of PTNBs. Thus, this study assessed the proximate composition of HM, lyophilized HM, and hydrated lyophilized HM. For that matter, mature HM of 20 mothers was collected and sampled into 3 sample pools (HM, lyophilized HM, and hydrated lyophilized HM) for further analysis to define their proximate composition. Results demonstrated that lyophilization increased by 8-fold ash, protein, lipid, and carbohydrate content, and energy values compared to HM. Moreover, dilution of 1 g of lyophilized HM with 3.5 g of water was proven ideal for babies weighing up to 1.5 kg, as it provides macronutrient concentrations that approach the recommended nutritional needs. Furthermore, lyophilized HM displayed potential as a possible replacement of infant formulas since, regarding macronutrients, it can supply the nutritional needs of PTNBs.

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Section: Reconstituted Human Milk Versus Infant Formulasmentioning

confidence: 99%