Lower waist circumference in mildly-stunted adolescents is associated with elevated insulin concentration

Clemente, Ana Paula Grotti; Santos, Carla Danusa da Luz; Martins, Vinícius Gomes; Albuquerque, Maria Paula de; Fachim, Mariana Belluca; Sawaya, Ana Lydia

doi:10.1016/j.jped.2014.01.015

Cited by 4 publications

(2 citation statements)

References 23 publications

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“…Additionally, a recent study showed the presence of insulin resistance among Indian undernourished rural population that was improved after six months of food supplementation [66] . On the other hand, Clemente et al [67] observed higher serum insulin levels in stunted Brazilian children. These inconsistent findings could be due to different degree of malnutrition, ethnicity, age ranges of participants, pubertal stage, body weight status, as well as methods of biochemical analyses.…”

Section: Discussionmentioning

confidence: 92%

Evaluation of insulin-like growth factor-1, total ghrelin, and insulin resistance in nutritionally stunted Egyptian children

Abdou

El-Boghdady

El-Maksoud

et al. 2019

Bulletin of Faculty of Pharmacy, Cairo University

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Stunting represents a worldwide nutritional problem, which has many negative effects on child health and development. This study aimed to investigate the levels of insulin-like growth factor-1(IGF-1), total ghrelin and insulin resistance, as well as certain micronutrients affecting children growth and skeletal maturity in nutritionally stunted Egyptian children. Stunted children were selected to have height for age Z score (HAZ) <-2 standard deviation, whereas, control children were selected to have HAZ >-2. Stunted children were further classified according to weight for age Z score into normal and underweight groups. All stunted children exhibited significantly lower serum levels of IGF-1, Ca, and Mg compared to normal control children. Additionally, both normal weight and underweight groups showed insignificantly higher total ghrelin levels than the control values. Only stunted underweight children showed significantly lower serum Zn levels compared to control children. Meanwhile, no significant differences were observed in serum glucose and insulin levels, pancreatic beta cell function and insulin resistance between different study groups. In conclusion, these findings highlight the importance of early detection of abnormalities in growth hormone / IGF-1 axis and micronutrients levels in hope that appropriate intervention strategies could improve their status to obtain full growth potential in nutritionally stunted Egyptian children.

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Section: Discussionmentioning

confidence: 92%

Evaluation of insulin-like growth factor-1, total ghrelin, and insulin resistance in nutritionally stunted Egyptian children

Abdou

El-Boghdady

El-Maksoud

et al. 2019

Bulletin of Faculty of Pharmacy, Cairo University

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show abstract

“…Quando crianças foram avaliadas pelo parâmetro CC no Canadá e no Brasil, observou-se que o percentual de crianças que apresentaram CC elevada indicou aumento de risco cardiovascular em ambos os sexos, porém, foi mais prevalente no sexo masculino (19)(20)(21) . As médias de CC encontradas no presente estudo foram também significativamente superiores no sexo masculino, resultados similares ao encontrados por outros estudos (22,23) .…”

Section: Discussionunclassified

Associação de indicadores antropométricos e pressão arterial com a relação cintura/estatura em escolares

Christmann

Bosco²,

Adami

2016

RBPS

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Association of anthropometric indicators and blood pressure with waist-to-height ratio in school children Asociación entre indicadores antropométricos y presión arterial con el índice cintura-altura de escolares RESUMO Objetivo: Associar os indicadores antropométricos e pressão arterial com a relação cintura/ estatura em escolares. Métodos: Estudo transversal envolvendo 342 escolares de 6 a 11 anos, de um município do Rio Grande do Sul, Brasil, com coleta realizada de março a novembro de 2014, aferindo peso, altura, pressão arterial sistólica e diastólica (PAS/PAD), circunferência da cintura (CC) e relação cintura/estatura (RCE). Utilizaram-se os testes estatísticos de t-Student e Qui-quadrado, e nível de significância de 5% (p≤0,05). Resultados: Do total de escolares, 54,4% (n=186) eram do sexo feminino, 32,7% (n=112) estavam com sobrepeso e 5% (n=17) eram obesos, de acordo com a classificação do IMC; 11,1% (n=38) eram pré-hipertensos, 5% (n=17) estavam com HAS estágio I, na classificação da PAS/PAD geral; 37,1% (n=127) tinham CC elevada e 23,4% (n=80), RCE elevada. Não foram encontrados escolares com HAS estágios II e III na amostra estudada. Magreza e eutrofia (p≤0,01), PAS e PAD normal (p≤0,01) e CC normal (p≤0,01) foram significativamente associadas à classificação de RCE normal, assim como sobrepeso e obesidade (p≤0,01), pré-hipertensão (p≤0,01) e CC elevada (p≤0,01) foram significativamente associados à RCE elevada. Conclusão: Concluiu-se que o sexo masculino apresentou medidas antropométricas significativamente superiores às do sexo feminino. Magreza, eutrofia, pressão arterial sistêmica e circunferência de cintura normais foram associadas à relação cintura/estatura (RCE) normal, enquanto sobrepeso, obesidade, pré-hipertensão e circunferência de cintura elevada estiveram associados à classificação elevada de RCE.

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Endocrine Changes in Undernutrition, Metabolic Programming, and Nutritional Recovery

Martins¹,

Albuquerque²,

Sawaya³

2017

Handbook of Famine, Starvation, and Nutrient Deprivation

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Lower waist circumference in mildly-stunted adolescents is associated with elevated insulin concentration

Abstract: The results presented herein suggest that an increase in plasma insulin is one of the primary metabolic modifications in stunted individuals, and that this alteration could be identified at a lower WC cut-off point than in non-stunted counterparts.

Cited by 4 publications

References 23 publications

Evaluation of insulin-like growth factor-1, total ghrelin, and insulin resistance in nutritionally stunted Egyptian children

Evaluation of insulin-like growth factor-1, total ghrelin, and insulin resistance in nutritionally stunted Egyptian children

Associação de indicadores antropométricos e pressão arterial com a relação cintura/estatura em escolares

Endocrine Changes in Undernutrition, Metabolic Programming, and Nutritional Recovery

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