Seroprevalence of transfusion-transmissible infectious diseases at a hemotherapy service located in southwest Bahia, Brazil

Rebouças, Kelly Almeida Andrade Ferreira; Narici, Flávio Marinho; Santos, Manoel Neres; Neres, Nayara Silva de Macêdo; Oliveira, Márcio Vasconcelos; Souza, Cláudio Lima

doi:10.1016/j.htct.2019.03.007

Cited by 11 publications

(18 citation statements)

References 14 publications

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“…In this study, the majority (38.39%) of blood donors were age range 28–37 years, which was analogous to the prvious studies outcomes [ 15 – 17 ]. On the other hand, the percentage of overall donors tested psotive for TTIs (15.91%) or, in particular, anti-HIV1/2 (2.61%), anti-HCV (1.40%), HBVsAg (5.57%), anti- T. palladium (5.72%), and MI (0.59%) are much higher in this study compared with the findings of many previous studies [ 3 , 8 , 15 , 18 ]. In contrast, there are lowered compared to Bisetegen FS et al, Study [ 9 ].…”

Section: Main Textcontrasting

confidence: 71%

“…Although these outcomes have also strengthened by the findings of multivariate logistic regression, Pearson Chi -Squared analysis found that the higher prevalence among the Rabak residents was only occurred by the significant greater frequency of HBVsAg, and anti- T. palladium . Formerly, Rebouças KA et al, study has documented similar probability of TTIs among age groups [ 18 ], which could be related to the dissimilarity in the genetic constitution, immunity of individuals, and the magnitude of risk factors that may affect the individual’s susceptibility to TTIs. Likewise, it has known that the period of living in the infected community increases the likelihood of acquiring illnesses.…”

Section: Main Textmentioning

confidence: 99%

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Transfusion transmitted infections among male blood donors of White Nile State, Sudan: Screening of the current seroprevalence and distribution

Ahmed¹,

Essa²,

Almugadam³

et al. 2020

BMC Res Notes

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Objective Our study planned to investigate the current positivity rate and distribution of the serologic markers of TTIs among male blood donors of the White Nile state, Sudan. Results The overall reported seropositive cases of TTIs was 15.91%, and percentages of anti-Human immunodeficiency virus 1/2 (anti-HIV1/2), Hepatitis B virus surface antigen (HBVsAg), anti-Hepatitis C virus (anti-HCV), and anti-Treponema palladium (anti-T. palladium) were 2.61%, 5.57%, 1.40%, and 5.72%, respectively. Out of 10897 donors examined, 0.59% had a serological sign of multiple infections. Furthermore, the odds of testing positive for TTIs were higher in the 28–37 age group (OR: 2.620, 95% CI: 2.324–2.955) and lower in the 38–47 age group (OR: 0.671, 95% CI: 0.567–0.794) compared to individuals of 18–27 years old. Likewise, it is more in individuals of Kosti (OR: 1.122, 95% CI: 0.987–1.277) and Rabak (OR: 1.354, 95% CI: 1.188-1.543) localities compared to Al Douiem locality. Anti-HIV/anti-T. palladium (27.70%) and anti-HIV/HBVsAg (23.07%) were the most frequently detected serologic markers of co-infections, P = 0.002.

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Section: Main Textcontrasting

confidence: 71%

Section: Main Textmentioning

confidence: 99%

Transfusion transmitted infections among male blood donors of White Nile State, Sudan: Screening of the current seroprevalence and distribution

Ahmed¹,

Essa²,

Almugadam³

et al. 2020

BMC Res Notes

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“…Multiple studies have addressed HTLV prevalence in Brazil and Argentina revealing regions of high endemicity. In the former, the highest prevalence was demonstrated in the North-North East region, in particular in Salvador de Bahia, ranging from 0.046% to 1.8% [ 303 , 306 , 308 , 309 , 310 , 312 , 313 , 319 , 320 , 356 , 357 , 358 , 359 , 360 , 361 , 362 , 363 , 364 , 365 , 366 ], with slightly higher prevalence in specific villages with African characteristics, such as Piaui (2.24%) [ 359 ], Taquarendi (3.85%), Junco (1.23%), Alegre (1.56%) [ 363 ] and Marajó Island (1–2.06%) [ 366 ]. In the South and South Eastern regions, HTLV prevalence ranged from 0.02% to 1.5% [ 302 , 303 , 305 , 318 , 321 , 322 , 358 , 367 , 368 , 369 , 370 ].…”

Section: Human T-cell Lymphotropic Virusmentioning

confidence: 99%

Lymphotropic Viruses EBV, KSHV and HTLV in Latin America: Epidemiology and Associated Malignancies. A Literature-Based Study by the RIAL-CYTED

Chabay

Lens

Hassan

et al. 2020

Cancers

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The Epstein–Barr virus (EBV), Kaposi sarcoma herpesvirus (KSHV) and human T-lymphotropic virus (HTLV-1) are lymphomagenic viruses with region-specific induced morbidity. The RIAL-CYTED aims to increase the knowledge of lymphoma in Latin America (LA), and, as such, we systematically analyzed the literature to better understand our risk for virus-induced lymphoma. We observed that high endemicity regions for certain lymphomas, e.g., Mexico and Peru, have a high incidence of EBV-positive lymphomas of T/NK cell origin. Peru also carries the highest frequency of EBV-positive classical Hodgkin lymphoma (HL) and EBV-positive diffuse large B cell lymphoma, not otherwise specified (NOS), than any other LA country. Adult T cell lymphoma is endemic to the North of Brazil and Chile. While only few cases of KSHV-positive lymphomas were found, in spite of the close correlation of Kaposi sarcoma and the prevalence of pathogenic types of KSHV. Both EBV-associated HL and Burkitt lymphoma mainly affect young children, unlike in developed countries, in which adolescents and young adults are the most affected, correlating with an early EBV seroconversion for LA population despite of lack of infectious mononucleosis symptoms. High endemicity of KSHV and HTLV infection was observed among Amerindian populations, with differences between Amazonian and Andean populations.

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“…Most inhabitants of the Caribbean region are of African ancestry; in fact, HTLV-1 prevalence has been found to be higher in areas populated with inhabitants of African descent in comparison with those inhabited by people of mixed and white descent. This is the case of Brazil, where the prevalence of HTLV-1/2 in blood donors is heterogeneous, ranging from 0.04 to 1% [5,[16][17][18][19][20][21][22] and a large study on Brazilian blood donors showed that regional differences in HTLV-1 prevalence are probably due to the ethnic origin of the underlying population. A higher prevalence in colored donors (2.14/1,000), versus mixed-race donors (1.58/1,000), or white donors (0.79/1,000) was shown [5,15].…”

Section: Resultsmentioning

confidence: 99%

Seroprevalence and Trends of HTLV-1/2 among Blood Donors of Santo Domingo, Dominican Republic, 2012-2017

Eusebio‐Ponce¹,

Candel²,

Paulino-Ramírez³

et al. 2020

Rev Esp Quimioter

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Objectives. Being a Caribbean country, the Dominican Republic is considered endemic for HTLV-1. Viral screening in blood banks is recommended for this blood borne infection. The purpose of this work is to analyze the seroprevalence and trends of HTLV-1/2 in the Dominican Republic blood donors; it is focused on Santo Domingo, the capital of the country, which has the largest blood donation activity. We also aim at comparing our findings with published data from neighboring countries. Patients and methods. We performed a retrospective cross-sectional study of 10 blood centers of Santo Domingo, which reported HTLV and the other blood-transmitted infections in full. They represent more than 40% of the province’s blood donations. Annual seroprevalence of HTLV-1/2, period prevalence (2012-2017), and time trend were determined. Results. A total of 352,960 blood donations were evaluated. The HTLV-1/2 period prevalence was 0.26% (929/352,960)(95% CI: 0.24–0.28%). We also found a marked predominance of replacement donation (90.4%) in comparison to voluntary contributions (9.6%). Therefore, this blood donor study may provide clues on the general prevalence of the infection. Conclusions. Seroprevalence of HTLV-1/2 in blood donors of Santo Domingo, Dominican Republic, showed a relatively low and steady trend in the studied period.

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Seroprevalence of transfusion-transmissible infectious diseases at a hemotherapy service located in southwest Bahia, Brazil

Cited by 11 publications

References 14 publications

Transfusion transmitted infections among male blood donors of White Nile State, Sudan: Screening of the current seroprevalence and distribution

Transfusion transmitted infections among male blood donors of White Nile State, Sudan: Screening of the current seroprevalence and distribution

Lymphotropic Viruses EBV, KSHV and HTLV in Latin America: Epidemiology and Associated Malignancies. A Literature-Based Study by the RIAL-CYTED

Seroprevalence and Trends of HTLV-1/2 among Blood Donors of Santo Domingo, Dominican Republic, 2012-2017

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