“…In this prospective, quaternary ammonium salts of 2-halo-4,6-dialkoxy-1,3,5-triazines, e.g., 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMTMM(Cl)), (see Figure 2), represent a valid alternative for the formation of amide bonds both in organic and water solvent [20,21,[32][33][34][35][36][37][38][39]. In the last years, DMTMM(Cl), commonly known as DMTMM, has found many applications as dehydro-condensation agent for the synthesis of amides and esters [36,40], collagen cross-linking [7,21,38], preparation of carboxymethylcellulose based films [39], amine grafting on hyaluronan [20,40,41], and peptide synthesis [42]. Additionally, the synthesis of a library of 2-(4,6-dimethoxy-1,3,5-triazinyl)trialkyl ammonium salts (DMT-Ams(X), X: Cl − or ClO 4 − ) and their activity as dehydro-condensation agents for the synthesis of amides, has been reported by Kunishima et al [43] (Figure 2).…”