Petiveria alliacea, a plant used in Afro-Brazilian smoke rituals, triggers pulmonary inflammation in rats

Alves, Thiago Cagliumi; Rodrigues, Eliana; Lago, João Henrique G.; Prado, Carla M.; Girardi, Carlos Eduardo Neves; Hipólide, Débora Cristina

doi:10.1016/j.bjp.2019.06.005

Cited by 7 publications

(3 citation statements)

References 43 publications

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“…It has been reported that sulfide derivatives such as diethyl sulfide and propyl disulfide, including terpene derivatives, have an attractive action on bees [40,41]. These compounds are similar to what is contained in the extract of A. sativum, according to what was reported by Yakin [35] and Duran [10].…”

Section: Dynamics Of Vegetative Shoots (A) and Floral Shoots (B) That...supporting

confidence: 60%

Technological Development in the Use of <em>Allium sativum</em> Aqueous Extracts in the Agricultural Field

Flores¹,

Conesa²,

López³

et al. 2023

Organic Fertilizers - New Advances and Applications [Working Title]

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The advance in agricultural technology could increase their commercialization, being the agronomic management for each crop an alternative. The management of natural products is a relevant and responsible need, in order to improve the quality and production of food, and to protect the agro-ecosystem biodiversity. Therefore, the aim of this chapter is to present our five-year study advances in mango and rambutan agronomic management with aqueous extract of Allium sativum and the use of natural adherent such as Melipona solani honey that improves the function of the components in the biological processes of the crop. Our results showed that this aqueous extract promotes the emission of vegetative and floral shoots, increases flower development, works as an attractant for pollinators, promotes fruit set, stimulates fruit growth, acts as an insecticide to control thrips and mealybugs and stimulates the production of defense metabolites, such as polyphenol compounds. The use of stingless bee honey as an adherent and the aqueous extract of A. sativum could be a key to potentiate the function of its components in leaves, panicles, flowers and fruits.

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Section: Dynamics Of Vegetative Shoots (A) and Floral Shoots (B) That...supporting

confidence: 60%

Technological Development in the Use of <em>Allium sativum</em> Aqueous Extracts in the Agricultural Field

Flores¹,

Conesa²,

López³

et al. 2023

Organic Fertilizers - New Advances and Applications [Working Title]

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“…However, except for Petiveria alliacea, none of the 16 plants had these properties investigated in the context of the ritualistic use. After simulating the route of administration of the site where the ritual is performed, Alves et al [89] found no effect on locomotor activity or anxiety-like behavior of P. alliacea in laboratory animals, and called the attention to possible negative effects of such administration.…”

Section: Discussionmentioning

confidence: 99%

“The plants have axé”: investigating the use of plants in Afro-Brazilian religions of Santa Catarina Island

Pagnocca

Zank

Hanazaki

2020

J Ethnobiology Ethnomedicine

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Background: Cultural and religious practices of African origin have decisively influenced traditional health practices in the Americas since the African diaspora. Plants are core elements in the religions of African origin. Compared with other parts of Brazil where the Afro-Brazilian presence is widely recognized, in Southern Brazil, these cultural practices are often socially invisible. Yet, there are several terreiros of three Afro-Brazilian religions: Candomblé, Umbanda, and Ritual deAlmas e Angola. We hypothesize that the importance of plants in Afro-Brazilian religions is linked not only to spiritual and magical issues but also to the medicinal properties of these plants. We seek to answer the following questions: (a) Which plants are used in the terreiros and what are their indications for use?; (b) Are there plants that stand out culturally in these religious groups?; and (c) What is the importance of the adaptive maintenance and replacement process in the use of plants in these religions, considering the Neotropical and African plants? Methods: We performed a census of the existing terreiros on the Island of Santa Catarina to collect information on the knowledge and use of plants. In all terreiros that consented to participate in the research, we collected data through semi-structured interviews, guided tours for plant collection, and participant observation. We identified the botanical species through expert consultations and botanical literature. Results: We interviewed 27 spiritual leaders, who cited 93 plants belonging to 86 botanical species. We identified 14 categories of use, with emphasis on liturgical ritual use (59%), general and unspecified diseases (32%), and digestive diseases (27%). In most liturgics uses, direct contact between plant and patient occurs, as in the case of bathing and the cleansing use of smoke. Sixteen plants were cited in all terreiros, configuring a set of species that can be considered as culturally important plants for these religious groups. Conclusions: These groups have extensive knowledge about a highly consensual set of therapeutic plants that should be further investigated pharmacologically to understand the effect of their external use. Also, we emphasize the importance of recognizing and valuing this ancestral Afro-Brazilian knowledge and learning also from these people about their broader vision of health which also adds more spirituality in health care.

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“…Petiveria alliacea is a perennial plant widely found in Indonesia and empirically used as a folk medicine to treat various diseases, such as diabetes, bleeding cough, anti-inflammation, and immunomodulatory. Several studies revealed that P. alliacea has anti-inflammatory [12][13][14][15] and antioxidant activities [16]. All parts of P. alliacea are available for use in treatment from oxidative damage of cells [17].…”

Section: Introductionmentioning

confidence: 99%

The self-nanoemulsifying drug delivery system of Petiveria alliacea extract reduced the homeostatic model assessment-insulin resistance value, interleukin-6, and tumor necrosis factor-α level in diabetic rat models

2021

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Background and Aim: Metaflammation plays a significant role in the pathogenesis, development, and complication of diabetes mellitus (DM). This inflammation is associated with insulin resistance. Therefore, the inflammatory pathways have been targeted for pharmacological treatment. Petiveria alliacea can decrease blood glucose levels and has anti-inflammatory and antioxidant activities; however, there are still insufficient data regarding its efficacy for the treatment of DM. This study aimed to investigate the effect of the self-nanoemulsifying drug delivery system (SNEDDS) of P. alliacea leaf extract on the homeostatic model assessment (HOMA)-insulin resistance (IR) value and interleukin (IL)-6 and tumor necrosis factor-α (TNF-α) levels in a streptozotocin (STZ)-induced diabetic rat model. Materials and Methods: Thirty-five diabetic rat models were randomly divided into five groups. The first group received the SNEDDS of P. alliacea leaf extract at a dose of 50 mg/kg body weight (BW), the second group received it at a dose of 100 mg/kg BW, the third group received it at a dose of 200 mg/kg BW, the fourth group received 18 mg of metformin, and the fifth group only received the SNEDDS formula. The treatment was administered once a day, orally, for 14 days. On the 15th day after treatment, the rats were sacrificed to obtain blood samples for cardiac examination. The IL-6, TNF-α, and insulin levels in the serum were measured using the enzyme-linked immunosorbent assay method. The HOMA-IR value was calculated using a formula. Results: The mean IL-6 and TNF-α levels were low in the group that received the SNEDDS of P. alliacea leaf extract. There was no significant difference in the insulin level in all treatment and control groups. However, a significant difference in the HOMA-IR value was noted between the group that received the SNEDDS of P. alliacea leaf extract and metformin and the group that did not receive treatment (p<0.05). Conclusion: The SNEDDS of P. alliacea leaf extract reduced the HOMA-IR value and suppressed the TNF-α and IL-6 levels in the STZ-induced diabetic rat model.

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Petiveria alliacea, a plant used in Afro-Brazilian smoke rituals, triggers pulmonary inflammation in rats

Cited by 7 publications

References 43 publications

Technological Development in the Use of <em>Allium sativum</em> Aqueous Extracts in the Agricultural Field

Technological Development in the Use of <em>Allium sativum</em> Aqueous Extracts in the Agricultural Field

“The plants have axé”: investigating the use of plants in Afro-Brazilian religions of Santa Catarina Island

The self-nanoemulsifying drug delivery system of Petiveria alliacea extract reduced the homeostatic model assessment-insulin resistance value, interleukin-6, and tumor necrosis factor-α level in diabetic rat models

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