Chemical characterization, antioxidant and anti-HIV activities of a Brazilian propolis from Ceará state

Silva, Caroline Cristina Fernandes da; Salatino, Antônio; Motta, Lucimar Barbosa; Negri, Giuseppina; Salatino, Maria Luiza Faria

doi:10.1016/j.bjp.2019.04.001

Cited by 31 publications

(23 citation statements)

References 77 publications

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“…Considering the high plant diversity of the Brazilian biomes Martins, 2000, 2002;Silva et al, 2000Silva et al, , 2003, this approach could be extremely useful for identifying the botanical composition of propolis from different sources. This knowledge is important because the local flora influences both the diversity and the activities of propolis (Teixeira et al, 2003(Teixeira et al, , 2005Salatino et al, 2005;Toreti et al, 2013;Freitas et al, 2017;Bankova et al, 2018;Silva et al, 2019).…”

Section: Comparison Of the Methacrylate Embedding Technique And The Cmentioning

confidence: 99%

“…Propolis is a bee product consisting mostly of beeswax and resin, which is collected by worker bees from plant buds or exudates (Salatino et al, 2019). A vast scientific literature has described various aspects of propolis, including the diversity of resin sources and the biological activities attributed to propolis extracts and isolated constituents (see Teixeira et al, 2003Teixeira et al, , 2005Salatino et al, 2005;Toreti et al, 2013;Freitas et al, 2017;Bankova et al, 2018;Silva et al, 2019). Maciel et al (2002) noted that the medicinal properties of propolis (i.e., anti-inflammatory, antioxidant, and antimicrobial properties) have attracted the interest of researchers from varied fields of study (e.g., botany, pharmacology, phytochemistry), whose research has enriched our knowledge of natural medicinal sources.…”

mentioning

confidence: 99%

“…Because propolis is mainly composed of compounds produced by plants, its chemical profile is derived from the contribution of the different plant species providing the resin (Bankova et al, 2018;Silva et al, 2019). Several factors influence the botanical composition of propolis, such as climatic conditions of the production area and the phenological variation of the vegetative species (Wink, 1990;Huang et al, 2014;Anjum et al, 2018).…”

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confidence: 99%

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Methacrylate: An alternative fixing agent for identifying the botanical origin of propolis

2019

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PremiseA new technique was developed to identify the botanical origin of propolis, a resin‐like material made by bees by mixing saliva and beeswax with plant buds and exudates, using methacrylate for permanent slide preparation.Methods and ResultsPropolis samples were fixed in methacrylate to produce permanent slides. The anatomical structures of the plant fragments in the methacrylated propolis were compared with propolis slides prepared using conventional techniques that consist of propolis sediment obtained during a series of solvent reactions, filtration, and centrifugations, which cost a similar amount to produce. The techniques resulted in qualitative differences between the slides obtained. The methacrylated propolis sections allowed the detailed observation and identification of plant anatomical structures that were obscured in samples prepared using the conventional procedure. This clarity enabled the detailed evaluation of valuable taxon‐diagnostic characters in a permanent slide, which can also be used for histochemical tests.ConclusionsThe methacrylated embedding of propolis is an affordable technique that could be implemented as a routine laboratory procedure. This new technique enables the efficient determination of the botanical origin of propolis.

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Section: Comparison Of the Methacrylate Embedding Technique And The Cmentioning

confidence: 99%

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confidence: 99%

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Methacrylate: An alternative fixing agent for identifying the botanical origin of propolis

2019

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“…The antiviral effect of NAR has been studied in several viruses, such as dengue ( 25 , 26 ), hepatitis C ( 27 ), zika ( 28 ), chikungunya ( 29 ), Semliki Forest ( 30 ), herpes simplex 1 and 2 ( 31 ), yellow fever ( 32 ), and human immunodeficiency virus ( 33 ). Several in vitro studies have highlighted NAR’s antiviral effect in pre-infection and post-infection ( 28 ).…”

Section: Introductionmentioning

confidence: 99%

Perspective: The Potential Effects of Naringenin in COVID-19

et al. 2020

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Coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), was declared a pandemic by the World Health Organization in March 2020. Severe COVID-19 cases develop severe acute respiratory syndrome, which can result in multiple organ failure, sepsis, and death. The higher risk group includes the elderly and subjects with pre-existing chronic illnesses such as obesity, hypertension, and diabetes. To date, no specific treatment or vaccine is available for COVID-19. Among many compounds, naringenin (NAR) a flavonoid present in citrus fruits has been investigated for antiviral and anti-inflammatory properties like reducing viral replication and cytokine production. In this perspective, we summarize NAR potential anti-inflammatory role in COVID-19 associated risk factors and SARS-CoV-2 infection.

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“…Propolis is a natural compound defined as a complex resin matrix produced by bees from a mixture of exudates from different plants, wax and salivary secretions; it has major applications in the food, pharmaceutical and cosmetic industries [ 1 , 2 ]. Numerous studies have demonstrated its antioxidant [ 3 , 4 ], antimicrobial [ 5 , 6 ], anti-inflammatory [ 7 , 8 ] and antitumor [ 7 , 8 ] activities, among others [ 9 , 10 , 11 , 12 ]. These activities are attributed to the bioactive chemical compounds in propolis, such as phenolic acids, flavonoids, terpenes and sesquiterpenes [ 13 , 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

Supercritical Extraction of Red Propolis: Operational Conditions and Chemical Characterization

et al. 2020

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The objective of this study was to determine the best operational conditions for obtaining red propolis extract with high antioxidant potential through supercritical fluid extraction (SFE) technology, using carbon dioxide (CO2) as the supercritical fluid and ethanol as the cosolvent. The following parameters were studied: overall extraction curve, S/F (mass of CO2/mass of sample), cosolvent percentage (0, 1, 2 and 4%) and global yield isotherms as a function of different pressures (250, 350 and 450 bar) and temperatures (31.7, 40 and 50 °C). Within the investigated parameters, the best conditions found were an S/F of 131 and the use of ethanol at the highest concentration (4% w/w), which resulted in higher extract yields and higher content of antioxidant compounds. Formononetin, the main biomarker of red propolis, was the compound found at the highest amounts in the extracts. As expected, the temperature and pressure conditions also influenced the process yield, with 350 bar and 40 °C being the best conditions for obtaining bioactive compounds from a sample of red propolis. The novel results for red propolis found in this study show that it is possible to obtain extracts with high antioxidant potential using a clean technology under the defined conditions.

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Chemical characterization, antioxidant and anti-HIV activities of a Brazilian propolis from Ceará state

Cited by 31 publications

References 77 publications

Methacrylate: An alternative fixing agent for identifying the botanical origin of propolis

Methacrylate: An alternative fixing agent for identifying the botanical origin of propolis

Perspective: The Potential Effects of Naringenin in COVID-19

Supercritical Extraction of Red Propolis: Operational Conditions and Chemical Characterization

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