Simultaneous determination of five N-alkylamides in the root of Anacyclus pyrethrum by HPLC and profiling of components in its methanolic root extract by UPLC/Q-TOF-MS

Anacyclus Pyrethrum: A Brief Overview of Phytochemistry, Traditional Uses, and Potential Therapeutic Properties

“…Work-up on the ethanolic aqueous extracts of the bloom heads, leaflets and seeds of AP validate the existence of 20 composites disclosed by GC-MS, tyramide, and isovaleric acid are among the ingredients. These amalgamations were Ist investigated in addition to the specific amalgamation likewise alkylamides ((2,4)-n-isobutyl-2,4-undecadien-8,10-diynamide, n-isobutyl-dodeca-2,4,8,10-tetraenamide, n-isobutyl-2,4-octadiene-6-monoynamide, nisobutyl-2,4-heptadiene-6-monoynamide and nisobutyl-2,6,8-datrieneamide) [36]. Furthermore, quantitative and qualitative research on AP methanolic extract concerned with n-alkyl amides is being conducted since they exhibit various fractionation routes that may be used to identify components here contained in the plant.…”

“…The research on natural oxygen inhibitors has focused on several studies on AP [30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47]. In an earlier discussion, the litterateur and his fellow workers debated the anti-oxidant effectiveness of MeOH extract, the aqueous extract & the Chl.…”

“…Additionally, someone's findings have demonstrated that A. pyrethrum's leaflet, grains, radicle, and florets heads have extremely significant anti-inflammatory effects on rat edoema. Inhibition in the oral therapy groups after an hour of treatment varied from 61% to 71% [36]. However, the proportion of resistance ranged from 60% to 82% and was higher in the groups that had percutaneous treatment Alkaloids (pellitorin), particularly alkylamides, may operate by decreasing neurogenic inflammation, whilst flavones have a diaphragm-stabilizing effect by lowering vasodilation, which increases the solidity and integrity of blood vessel walls [36,44].…”

Phytochemistry, Biological and Pharmacological Activities of the Anacyclus pyrethrum (L.) Lag: A Systematic Review

“…Given this approach, twenty-one compounds have been identified, including twenty n -alkylamide and one organic acid. Two components were first observed in this plant: (2 E ,7 Z )- n -isobutyl-2,7-tridecadiene-10,12-diynamide and (2 E ,6 Z ,8 E )- n -isobutyl-2,6,8-diatrinamide [ 44 ]. In addition, new compounds were identified through quadrupole ultra-high performance liquid chromatography-time-of-flight mass spectrometry (UPLC-Q-TOF-MS): dodeca-2 E ,4 E , E - trienoic acid-4-hydroxy phenylethylamide, tetradic acid–2 E -deni-8,10-denoic acid, undeca-2 E ,4 E -diene-8,10-diynoic acid 4-oh-phenylethylamide, tetradeca-2 E ,4 E -ne-trienoic-8,10-diynoicacid and tetradeca-2 E ,4 E -ne-trienoic acid [ 44 ].…”

Spanish chamomile (Anacyclus pyrethrum) and pyrethrum (Tanacetum cineraiifolium): organic and natural pesticides and treasure of medicinal herbs

“…Pyrethrins also have the advantage over other synthetic insecticides of being rapidly broken down upon exposure to light and air, are metabolized quickly, and can be used in the production of organic farm products, and they generally considered to be nonpolluting (Casida, 1990;Elliott, 1995).The plant Anacyclus pyrethrum consists of several N-alkylamides with pellitorine as main constituents, and its extracts are already commercially available with functional cosmeceutical claims (Veryser et al, 2014). Its root is widely used for treating various diseases in traditional Uygur medicine, particularly in the treatment of vitiligo (Ji et al, 2019). Rachida et al (2014) reported that A. pyrethrum roots widely used in Moroccan traditional medicine in treatment of teeth disease and in treatment of memory disorders, besides, a mixture of roots and milk added by honey is proposed as aphrodisiac, against the feminine infertility.…”