Some triterpenic compounds in extracts of Cecropia and Bauhinia species for different sampling years

Schmidt, Marcella Emilia Pietra; Pires, Fernanda Brum; Bressan, Lucas Paines; Silva, Fábio Vieira da; Lameira, O. A.; Rosa, Marcelo Barcellos da

doi:10.1016/j.bjp.2017.11.005

Cited by 11 publications

(16 citation statements)

References 59 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Summarizing, the total identified content of triterpenoids was greatest in lingonberry fruits (13,397.88 µg/g DW), followed by flowers (11,180.06 µg/g DW) and leaves (7020.25 µg/g DW). The sum of identified triterpenoids in lingonberry fruits and leaves was partly in line with the previous study, bearing in mind that the level of triterpenoids highly depends on geographical origin, harvesting time, and stage of maturity of raw material [31], thus driving the potential of further investigations.…”

Section: Application To Lingonberry Materialsmentioning

confidence: 98%

“…More complex triterpenoids include phytosterols with a predominant member of β-sitosterol [ 9 ]. Triterpenoids have been shown from various scientific studies to have a wide range of beneficial bioactivities, namely, chemopreventive, anti-inflammatory, antiviral, antihyperlipidemic, antidiabetic, hepatoprotective, antibacterial, antioxidant, and wound-healing properties [ 8 , 10 , 11 ]. Therefore, they constitute a source of interest as promising leading compounds for the development of new multi-targeting pharmaceuticals [ 5 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Optimization, Validation and Application of HPLC-PDA Methods for Quantification of Triterpenoids in Vaccinium vitis-idaea L.

Vilkickytė

Raudonė

2021

Molecules

View full text Add to dashboard Cite

Triterpenoids have regained much attention as promising multi-targeting bioactive agents of natural origin in the treatment of numerous disorders. Due to the high potential for phytopharmaceutical development, accurate qualitative and quantitative analysis of triterpenoids for screening and quality control is required. Vaccinium vitis-idaea L. (lingonberry) raw materials have aroused interest as a rich source of triterpenoids. However, currently, no validated, rapid, and easy-to-perform quantification method is available for the routine control of these compounds in lingonberries. This research aimed at developing and validating HPLC-PDA methods for the determination and screening of triterpenoids in extracts of lingonberry leaves, fruits, and flowers. The developed methods were deemed satisfactory by validation, which revealed acceptable analytical specificity, linearity (r2 > 0.9999), precision (RSD < 2%), trueness (94.70–105.81%), and sensitivity (LOD: 0.08–0.65 µg/mL). The real sample analysis demonstrated established methods applicability for quantification of 13 triterpenoids in lingonberries and emphasized differences between raw materials. Lingonberry fruits were distinguished by the richness of ursolic acid; lingonberry flowers by similar profile to fruits, but low content of neutral triterpenoids; whereas lingonberry leaves by the particularly high level of α-amyrin. Thus, the proposed methods proved to be reliable and applicable for quantification and routine analysis of triterpenoids in lingonberry samples.

show abstract

Section: Application To Lingonberry Materialsmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Optimization, Validation and Application of HPLC-PDA Methods for Quantification of Triterpenoids in Vaccinium vitis-idaea L.

Vilkickytė

Raudonė

2021

Molecules

View full text Add to dashboard Cite

show abstract

“…Cecropia ficifolia (leaves): This species has never been studied for its chemical compounds or biological activity but other species of the genus Cecropia (C. palmata and C. obtusa leaves) contained anti-HCV triterpenic compounds such as oleanolic acid (Schmidt et al, 2018;Kong et al, 2013).…”

Section: Scleria Microcarpa and Astrocaryum Jauarimentioning

confidence: 99%

Viral hepatitis in the Peruvian Amazon: Ethnomedical context and phytomedical resource

Roumy

Ruiz

Macedo

et al. 2020

Journal of Ethnopharmacology

View full text Add to dashboard Cite

Ethnopharmacological relevance An extensive ethnopharmacological survey was carried out in the Peruvian Amazonian district of Loreto with informants of various cultural origins from the surroundings of Iquitos (capital city of Loreto) and from 15 isolated riverine Quechua communities of the Pastaza River. A close attention was paid to the medical context and plant therapy, leading to the selection of 35 plant species (45 extracts). The extracts were tested for antiviral activity against HCV with counting of Huh-7 cellular death in case of toxicity, and cytotoxicity was evaluated in HepG2 cells.

show abstract

“…Resins have important applications in the paint and cosmetic industries [1,2]. Very recently, some of their constituents have attracted the attention of researchers because of their pharmacological effects as anti-inflammatory, antipruritic, anti-fungal and others [2,3,4,5,6]. Besides their industrial applications, resins have been used from ancient times for a variety of purposes including religious ceremonies and decoration of artworks.…”

Section: Introductionmentioning

confidence: 99%

“…Because of the bioactive properties of some triterpenes such as lupeol and amyrins, different methods have been recently proposed for their quantification in different plant materials [5,14,15,16,17]. The amount of sample in those studies was not limited, and therefore, the required sensitivity for quantification could be achieved after exhaustive sample treatments of large amounts of the samples, including multiple extractions, purification, solvent evaporation, and redissolution.…”

Section: Introductionmentioning

confidence: 99%

Quantitative Analysis of Terpenic Compounds in Microsamples of Resins by Capillary Liquid Chromatography

et al. 2019

View full text Add to dashboard Cite

A method has been developed for the separation and quantification of terpenic compounds typically used as markers in the chemical characterization of resins based on capillary liquid chromatography coupled to UV detection. The sample treatment, separation and detection conditions have been optimized in order to analyze compounds of different polarities and volatilities in a single chromatographic run. The monoterpene limonene and the triterpenes lupeol, lupenone, β-amyrin, and α-amyrin have been selected as model compounds. The proposed method provides linear responses and precision (expressed as relative standard deviations) of 0.6% to 17%, within the 0.5–10.0 µg mL−1 concentration interval; the limits of detection (LODs) and quantification (LOQs) were 0.1–0.25 µg mL−1 and 0.4–0.8 µg mL−1, respectively. The method has been applied to the quantification of the target compounds in microsamples. The reliability of the proposed conditions has been tested by analyzing three resins, white copal, copal in tears, and ocote tree resin. Percentages of the triterpenes in the range 0.010% to 0.16% were measured using sample amounts of 10–15 mg, whereas the most abundant compound limonene (≥0.93%) could be determined using 1 mg portions of the resins. The proposed method can be considered complementary to existing protocols aimed at establishing the chemical fingerprint of these kinds of samples.

show abstract

Some triterpenic compounds in extracts of Cecropia and Bauhinia species for different sampling years

Cited by 11 publications

References 59 publications

Optimization, Validation and Application of HPLC-PDA Methods for Quantification of Triterpenoids in Vaccinium vitis-idaea L.

Optimization, Validation and Application of HPLC-PDA Methods for Quantification of Triterpenoids in Vaccinium vitis-idaea L.

Viral hepatitis in the Peruvian Amazon: Ethnomedical context and phytomedical resource

Quantitative Analysis of Terpenic Compounds in Microsamples of Resins by Capillary Liquid Chromatography

Contact Info

Product

Resources

About