2017
DOI: 10.1016/j.bjp.2016.09.007
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Anti-inflammatory, and antinociceptive effects of Campomanesia adamantium microencapsulated pulp

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Cited by 18 publications
(12 citation statements)
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“…The C. adamantium, common in the Cerrado region, is already known to be rich in flavonoids and glycoflavonoids, and it is the chromatographic profile in TLC (Table 3) and in HPLC at 254 nm confirm that the etanolic extract of the leaves of these species has flavonoids at retention times 22.7 minutes, common for flavones in 34.5 minutes, the latter being common for chacons (Viscardi et al, 2016). The G. americana is one rubiaceae recognized for presented iridoids, but no peakes were observed below 8 minutes (Ono et al, 2005).…”
Section: Discussionmentioning
confidence: 78%
“…The C. adamantium, common in the Cerrado region, is already known to be rich in flavonoids and glycoflavonoids, and it is the chromatographic profile in TLC (Table 3) and in HPLC at 254 nm confirm that the etanolic extract of the leaves of these species has flavonoids at retention times 22.7 minutes, common for flavones in 34.5 minutes, the latter being common for chacons (Viscardi et al, 2016). The G. americana is one rubiaceae recognized for presented iridoids, but no peakes were observed below 8 minutes (Ono et al, 2005).…”
Section: Discussionmentioning
confidence: 78%
“…by gavage before exposure to one of the aforementioned inflammatory stimuli. The groups treated with dexamethasone by the subcutaneous route (s.c.) before receiving carrageenan or CFA were used as the "positive control," as the literature has demonstrated its efficacy in decreasing inflammatory and pain parameters in mice 33–35 . The negative controls received a vehicle before the inoculation of either of the inflammatory stimuli mentioned.…”
Section: Methodsmentioning
confidence: 99%
“…The groups treated with dexamethasone by the subcutaneous route (s.c.) before receiving carrageenan or CFA were used as the "positive control," as the literature has demonstrated its efficacy in decreasing inflammatory and pain parameters in mice. [33][34][35] The negative controls received a vehicle before the inoculation of either of the inflammatory stimuli mentioned. In two of the experimental models evaluated, a group named "naive" received only isotonic saline, instead of botryosphaeran or dexamethasone, and were inoculated with sterile isotonic saline instead of the inflammatory stimuli.…”
Section: Significance Statementmentioning
confidence: 99%
“…They have a succulent pulp with an acid-sweet flavor and are generally harvested in the field and consumed fresh (Oliveira;Costa & Proença, 2020). Among the main biological activities investigated in the species are: antimicrobial activity (Sá et al, 2018), antioxidant (Coutinho et al, 2010), anti-inflammatory and anti-nociceptive (Viscardi et al, 2017).…”
Section: Campomanesia Adamantiummentioning
confidence: 99%