Amazon emulsions as cavity cleansers: antibacterial activity, cytotoxicity and changes in human tooth color

Antimicrobial activity of copaiba oil (Copaifera ssp.) on oral pathogens: Systematic review

“…Copaiba oil, regardless of its genus, presented results of bactericidal and/or bacteriostatic effect. The most studied microorganisms against copaiba in this systematic review were Streptococcus mutans (Bardají et al, 2016;Bari et al, 2016;Conde et al, 2015;da Silva Moraes et al, 2016;Dias et al, 2015;Pieri et al, 2010;Pieri et al, 2012;Simões et al, 2016;Vasconcelos et al, 2008) followed by Streptococcus sanguinis (Bardají et al, 2016;da Silva Moraes et al, 2016;Simões et al, 2016;Vasconcelos et al, 2008), Streptococcus sobrinus (Bardají et al, 2016;Conde et al, 2015;da Silva Moraes et al, 2016;, Fusobacterium nucleatum (Bardají et al, 2016;, . Only one study demonstrated that copaiba oil presented antimicrobial effect similar or superior to the positive control used (Pieri et al, 2010).…”

“…It was observed in this analysis that all studies presented an unclear risk of bias for randomization, allocation concealment, and blinding of the evaluators. Hence, appropriate statistical analysis was performed only in five of the 11 featured items (Bardají et al , ; Bari et al , ; Dias et al , ; Pieri et al , ; Simões et al , ). In addition, in two other articles, the statistical analysis is not clear (Souza et al, ; Souza et al, ).…”

“…Four thousand five hundred and thirty-five titles/abstracts were retrieved from the search strategy, of which 2,474 were excluded for being duplicated. Based on the previously described criteria, 84 full titles were evaluated, of which 11 were selected (Bardají et al, 2016;Bari et al, 2016;Conde et al, 2015;da Silva Moraes et al, 2016;Dias et al, 2015;Pieri et al, 2010;Pieri, Mussi, Fiorini, Moreira, & Schneedorf, 2012;Simões et al, 2016;Vasconcelos, Veiga Júnior, Rocha, & Bandeira, 2008).…”

“…Different species of copaiba were used, as follows: Copaifera reticulate (Bardají et al, 2016), C. multijuga (Bari et al, 2016;Conde et al, 2015;Simões et al, 2016;Vasconcelos et al, 2008), C. langsdorffii (Dias et al, 2015;, C. oblongifolia (da Silva Moraes et al, 2016), C. officinalis (Pieri et al, 2010;Pieri et al, 2012). The studies were essentially in vitro, and the main test was minimum inhibitory concentration (Bardají et al, 2016;Bari et al, 2016;da Silva Moraes et al, 2016;Dias et al, 2015;Pieri et al, 2012;, followed by colony-forming units (Pieri et al, 2010;Simões et al, 2016;Vasconcelos et al, 2008). Minimum bactericidal concentration (da Silva Moraes et al, 2016), and minor inhibitory concentration of adhesion (Conde et al, 2015) were less used methodologies.…”

“…Hence, appropriate statistical analysis was performed only in five of the 11 featured items (Bardají et al, 2016;Bari et al, 2016;Dias et al, 2015;Pieri et al, 2010;Simões et al, 2016). In addition, in two other articles, the statistical analysis is not clear .…”