How to avoid the inappropriate use of antibiotics in upper respiratory tract infections? A position statement from an expert panel

Piltcher, Otávio Bejzman; Kosugi, Eduardo Macoto; Sakano, Eulália; Mion, Olavo; Testa, José Ricardo Gurgel; Romano, Fabrizio Ricci; Santos, Marco César Jorge dos; Francesco, Renata Cantisani Di; Mitre, Edson Ibrahim; Bezerra, Thiago Freire Pinto; Roithmann, Renato; Pádua, Francini G.M.; Valera, Fabiana Cardoso Pereira; Neto, José Faibes Lubianca; Sá, Leonardo Conrado Barbosa de; Pignatari, Shirley Shizue Nagata; Avelino, Melissa Ameloti Gomes; Caixeta, Juliana Alves de Souza; Anselmo‐Lima, Wilma Terezinha; Tamashiro, Edwin

doi:10.1016/j.bjorl.2018.02.001

Cited by 26 publications

(12 citation statements)

References 52 publications

(72 reference statements)

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“…Bacterial resistance is a phenomenon caused by the evolution or adaptation of microorganisms to antibiotics, through several molecular mechanisms [1]. Infections caused by multi-drug resistant microorganisms represent one of the major public health problems worldwide, both because of increased morbidity and mortality and due to high hospitalization costs [2,3].…”

Section: Introductionmentioning

confidence: 99%

Photoinduced Antibacterial Activity of the Essential Oils from Eugenia brasiliensis Lam and Piper mosenii C. DC. by Blue Led Light

Silva¹,

Castro²,

Dantas³

et al. 2019

Antibiotics

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The objective of this work was to evaluate the phytochemical composition and the antibacterial and antibiotic-modulating activities of the essential oils of Eugenia brasiliensis Lam (OEEb) and Piper mosenii C. DC (OEPm) singly or in association with blue LED (Light-emitting diode) light. The antibacterial and antibiotic-modulatory activities of the essential oils on the activity of aminoglycosides were evaluated to determine the minimum inhibitory concentration (MIC, μg/mL) in the presence or absence of exposure to blue LED light. The chemical analysis showed α-pinene and bicyclogermacrene as major constituents of OEPm, whereas α-muurolol was the main compound of OEEb. Both OEEb and OEPm showed MIC ≥ 512 μg/mL against the strains under study. However, the association of these oils with the blue LED light enhanced the action of the aminoglycosides amikacin and gentamicin. In conclusion, the association of aminoglycosides with the blue LED light and essential oils was effective against resistant bacteria.

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Section: Introductionmentioning

confidence: 99%

Photoinduced Antibacterial Activity of the Essential Oils from Eugenia brasiliensis Lam and Piper mosenii C. DC. by Blue Led Light

Silva¹,

Castro²,

Dantas³

et al. 2019

Antibiotics

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“…A utilização de antimicrobianos no cenário atual ocorre entre as diferentes classes e faixas etárias. Estima-se que mais de 50% das prescrições de antimicrobianos são consideradas inapropriadas e que os consumidores fazem o uso do medicamento fora do tempo recomendado, além de que dois terços se utilizam do medicamento sem prescrição e 90% o adquirem para um período estimado de três dias (9) . O resultado do uso desordenado desta classe medicamentosa acarreta no aparecimento de cepas de micro-organismos resistentes o que leva ao agravamento do caso clínico do paciente, dificultando assim o controle da doença (10) .…”

Section: Resultsunclassified

Uso Irracional De Antibióticos, Quais Os Fatores Envolvidos?

Costa¹,

Lima²,

Costa³

et al. 2021

RACF

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Introdução: os antibióticos são medicamentos utilizados no combate de doenças infecciosas de alto risco causadas por bactérias. De acordo com a Organização Mundial da Saúde, o Brasil é o país que mais consome de forma indiscriminada essa classe de medicamento. Objetivos: o trabalho teve por objetivo identificar a partir de uma análise na literatura a causa principal do uso irracional de antibióticos, apontar o principal agravante do uso indevido dessa classe e enfatizar a importância do papel do farmacêutico neste cenário. Métodos: a pesquisa foi realizada a partir de uma revisão integrativa, com busca eletrônica de artigos nas bases de dados BVS, SCIELO, PUBMED, CINHHL, através de descritores: "Uso irracional de antibióticos", "fatores da automedicação de antibióticos", "consequências do uso irracional de antibióticos" e "importância do farmacêutico" no período de 2010 a 2020. Resultados e discussão: com base no levantamento de dados, os principais fatores que levaram a automedicação de antimicrobianos foram o uso de prescrições antigas, alívio rápido de sintomas, dificuldade de acesso ao serviço de saúde pública e conhecimento prévio da patologia. Conclusão: O principal problema relacionado ao uso irracional de antimicrobianos foi a resistência bacteriana e foi possível observar que os autores reconhecem a importância do papel do farmacêutico na promoção da racionalização do uso deste medicamento. Palavras-chave: Antibiótico, resistência bacteriana, farmacêutico.

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“…Концентрация специфических антител в слизистой оболочке крайне низка ввиду проникновения вируса внутрь эпителиоцитов, где и происходит его размножение, запускаются каскады иммунного ответа и привлечение иммунных клеток с развитием очага воспаления [18]. ОВРС в большинстве случаев протекает легко [19], продолжительностью до 10 дней, и не требует назначения этиотропной терапии, однако для улучшения качества жизни и ускорения выздоровления пациента рекомендуется назначать терапию, направленную на снижение выраженности симптомов воспаления в полости носа [20].…”

Section: аналитический обзорunclassified

Topical therapy in the treatment of patients with acute rhinosinusitis in adults

Старостина¹,

Sivokhin²

2021

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Acute rhinosinusitis is one of the most common diseases in the world, characterized by acute inflammatory processes in the nasal cavity and paranasal sinuses, lasting less than 4 weeks. According to statistics, in Russia, this disease is recorded in 6–15% of the population annually, in European countries in every seventh person, while there is a tendency to an increase in the incidence. Acute viral rhinosinusitis has the highest incidence among all rhinosinusitis and occurs in most patients in a mild form, however, untimely treatment of inflammation of the nasal mucosa can lead to obstruction of the natural anastomoses, impaired physiological ventilation and drainage of the paranasal sinuses, stagnation of secretions with further development acute bacterial rhinosinusitis. The overuse of local vasoconstrictor drugs (intranasal decongestants) leads to the development of drug-induced rhinitis, long-term imbalance of autonomic innervation of the nasal mucosa and edema, called "rebound syndrome". In the article we consider the issues of etiology, pathogenesis, features of the course of rhinosinusitis. The principles of differential diagnosis of viral and bacterial rhinosinusitis are stated, taking into account the latest recommendations and research in this area. The features of the use of the most frequently used topical preparations in acute rhinosinusitis in the practice of an ENT doctor have been analyzed.

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How to avoid the inappropriate use of antibiotics in upper respiratory tract infections? A position statement from an expert panel

Cited by 26 publications

References 52 publications

Photoinduced Antibacterial Activity of the Essential Oils from Eugenia brasiliensis Lam and Piper mosenii C. DC. by Blue Led Light

Photoinduced Antibacterial Activity of the Essential Oils from Eugenia brasiliensis Lam and Piper mosenii C. DC. by Blue Led Light

Uso Irracional De Antibióticos, Quais Os Fatores Envolvidos?

Topical therapy in the treatment of patients with acute rhinosinusitis in adults

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