Treatment of tympanic membrane perforation using bacterial cellulose: a randomized controlled trial

Silveira, Fábio Coelho Alves; Pinto, Flávia Cristina Morone; Neto, Sílvio da Silva Caldas; Leal, Mariana de Carvalho; Cesário, Jéssica; Aguiar, José Lamartine de Andrade

doi:10.1016/j.bjorl.2015.03.015

Cited by 51 publications

(37 citation statements)

References 15 publications

(19 reference statements)

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“…Thus, the aforementioned study describing the duraplasty with BNC was an invasive application approach performed in humans. There are some other uses already applied in humans: a Brazilian study [117] continued the promising results of Kim et al [118] using BNC for tympanic membrane perforation. The special approach of this clinical study was the application in an infectious environment since only patients with tympanic perforations after an otitis media were included.…”

Section: In Vivo Scaffoldsmentioning

confidence: 94%

Nanocellulose as a natural source for groundbreaking applications in materials science: Today’s state

et al. 2018

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Nanocelluloses are natural materials with at least one dimension in the nano-scale. They combine important cellulose properties with the features of nanomaterials and open new horizons for materials science and its applications. The field of nanocellulose materials is subdivided into three domains: biotechnologically produced bacterial nanocellulose hydrogels, mechanically delaminated cellulose nanofibers, and hydrolytically extracted cellulose nanocrystals. This review article describes today's state regarding the production, structural details, physicochemical properties, and innovative applications of these nanocelluloses. Promising technical applications including gels/foams, thickeners/stabilizers as well as reinforcing agents have been proposed and research from last five years indicates new potential for groundbreaking innovations in the areas of cosmetic products, wound dressings, drug carriers, medical implants, tissue engineering, food and composites. The current state of worldwide commercialization and the challenge of reducing nanocellulose production costs are also discussed.

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Section: In Vivo Scaffoldsmentioning

confidence: 94%

Nanocellulose as a natural source for groundbreaking applications in materials science: Today’s state

et al. 2018

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“…The BC membrane is a wet dressing that favors hygiene, adheres well to the wound bed and spontaneously detaches once the wound is healed 13 . BC studies demonstrate that this is an innovative, effective, safe and low cost material 13,31 .…”

Section: Figure 1 Varicose Ulcer Initial Evaluation: A) Bacterial Cmentioning

confidence: 94%

Efficacy of bacterial cellulose membrane for the treatment of lower limbs chronic varicose ulcers: a randomized and controlled trial

Cavalcanti

Pinto

Oliveira

et al. 2017

Rev. Col. Bras. Cir.

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Objective: to evaluate the efficacy of Bacterial Cellulose (BC) membrane dressings in the treatment of lower limb venous ulcers. Methods: we carried out a prospective, randomized, controlled study of 25 patients with chronic venous ulcer disease in the lower limbs from the Angiology and Vascular Surgery Service of the Federal University of Pernambuco Hospital and from the Salgado Polyclinic of the County Health Department, Caruaru, Pernambuco. We randomly assigned patients to two groups: control group, receiving dressings with triglyceride oil (11 patients) and experimental group, treated with BC membrane (14 patients). We followed the patients for a period of 120 days. Results: There was a reduction in the wound area in both groups. There were no infections or reactions to the product in any of the groups. Patients in the BC group showed decreased pain and earlier discontinuation of analgesic use. Conclusion: BC membrane can be used as a dressing for the treatment of varicose ulcers of the lower limbs.

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“…A randomized controlled trial was conducted by Silveira et al (2016). Forty patients with TM perforation secondary to chronic otitis media were included and randomly assigned in two groups: experimental group (20), treated with BC graft and control group (20) treated with autologous temporal fascia (fascia).…”

Section: Tympanic Membranementioning

confidence: 99%

A multipurpose natural and renewable polymer in medical applications: Bacterial cellulose

Barud

Silva

Barud

et al. 2016

Carbohydrate Polymers

261

120

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Bacterial cellulose (BC) produced by some bacteria, among them Gluconacetobacter xylinum, which secrets an abundant 3D networks fibrils, represents an interesting emerging biocompatible nanomaterial. Since its discovery BC has shown tremendous potential in a wide range of biomedical applications, such as artificial skin, artificial blood vessels and microvessels, wound dressing, among others. BC can be easily manipulated to improve its properties and/or functionalities resulting in several BC based nanocomposites. As example BC/collagen, BC/gelatin, BC/Fibroin, BC/Chitosan, etc. Thus, the aim of this review is to discuss about the applicability in biomedicine by demonstrating a variety of forms of this biopolymer highlighting in detail some qualities of bacterial cellulose. Therefore, various biomedical applications ranging from implants and scaffolds, carriers for drug delivery, wound-dressing materials, etc. that were reported until date will be presented.

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Treatment of tympanic membrane perforation using bacterial cellulose: a randomized controlled trial

Abstract: Bacterial cellulose grafts promoted the closure of the tympanic membrane perforations, and were demonstrated to be innovative, effective, safe, minimally invasive, efficacious and to have a very low cost.

Cited by 51 publications

References 15 publications

Nanocellulose as a natural source for groundbreaking applications in materials science: Today’s state

Nanocellulose as a natural source for groundbreaking applications in materials science: Today’s state

Efficacy of bacterial cellulose membrane for the treatment of lower limbs chronic varicose ulcers: a randomized and controlled trial

A multipurpose natural and renewable polymer in medical applications: Bacterial cellulose

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