Laryngeal chondrosarcoma – Ten years of experience

Oliveira, José Fernando dos Santos; Branquinho, Francisco; Monteiro, Ana Raquel; Portugal, Maria Edite Correia Castro; Guimarães, Arnaldo

doi:10.1016/j.bjorl.2014.05.004

Cited by 32 publications

(51 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The primary site was most commonly the cricoid in 75% of cases, followed by the thyroid cartilage in 20%, and epiglottis or arytenoids in 5% [1]. Laryngeal chondrosarcomas appear around the age of 60 to 70 years with a clear predominance in males [1][2][3][4][5], as in our patient.…”

Section: Discussionmentioning

confidence: 60%

“…It accounts for 0.07 to 2% of laryngeal cancers and less than 1% of all sarcomas [1][2][3][4]. The primary site was most commonly the cricoid in 75% of cases, followed by the thyroid cartilage in 20%, and epiglottis or arytenoids in 5% [1].…”

Section: Discussionmentioning

confidence: 99%

“…Some authors suggest chronic inflammation or ischemic changes in a preexisting chondroma [1,4]. Repeated laryngeal trauma, as well as anterior neck irradiation and teflon injection are also implicated [3,4].…”

Section: Discussionmentioning

confidence: 99%

“…MRI studies show T1 low-signal and T2 high-signal with characteristic mosaic pattern without providing much additionnal information [2,3].…”

Section: Discussionmentioning

confidence: 99%

“…Total laryngectomy is indicated in cases of very advanced lesions, in case of infilration of surrounding tissues, in advanced degree differentiated cancers, or in cases of recurrence [3,4,9]. Lymphnode dissection is not usual, ganglion involvement rarely occurs [6].…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

Chondrosarcoma of the thyroid cartilage: a rare laryngeal malignancy

Ca¹,

Loum²,

Tb³

et al. 2017

Otorhinolaryngol Head Neck Sur

View full text Add to dashboard Cite

Laryngeal chondrosarcoma is a rare malignant tumor that arises from the cartilaginous structures of the larynx. It is a slow-growing neoplasm with high tendency to locoregional recurrence after treatment. Surgery is the primary treatment. Prognosis depends on histological differentiation degree and quality of surgical excision which can be very mutilating. Distant metastatis can occur in cases of histological high-grade tumors. From a new observation and a review of the literature, we discuss the clinical characteristics, therapeutic modalities and patient outcomes.

show abstract

Section: Discussionmentioning

confidence: 60%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…MRI studies show T1 low-signal and T2 high-signal with characteristic mosaic pattern without providing much additionnal information [2,3].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Chondrosarcoma of the thyroid cartilage: a rare laryngeal malignancy

Ca¹,

Loum²,

Tb³

et al. 2017

Otorhinolaryngol Head Neck Sur

View full text Add to dashboard Cite

show abstract

Laryngeal chondrosarcoma: A systematic review of 592 cases

et al. 2016

View full text Add to dashboard Cite

show abstract

Organ Preservation Strategies in Laryngeal Chondrosarcoma

et al. 2021

View full text Add to dashboard Cite

Objectives/Hypothesis: Laryngeal chondrosarcoma (LC) is a rare, slowly growing malignancy. The preferred treatment is laryngeal preservation surgery (LPS). Some patients may require multiple interventions or total laryngectomy (TL). We investigated risk factors for retreatment and TL, and assessed the impact of LPS on oncological and functional outcomes.Study Design: Case series Methods: We searched our institution database for LC. Tumor grading, localization, and margin status were tested as predictors of recurrence and organ preservation.Results: We included 21 patients (seven females, mean age 58 AE 12 years). LPS was applied in 20 (95.2%) of them as a primary procedure. Six patients were treated by transoral approach and 14 received "open-neck" LPS. Fifteen (71.4%) were operated only once, while six patients underwent a total of 15 adjunctive procedures. Additional operations were always performed for recurrence of tumors localized within the cricoid plate. The histological grading was G1 in 81% and G2 in 19%. However, two patients with a primary G1 LC showed a G2 recurrence. Reoperations for recurrence were more frequent among patients with G2 in respect to G1 histology (83% vs. 7%, P < .001). Fifty percent of G2 LC and 8% of G1 underwent TL (P < .05). Margin status had no influence on recurrence rate.Conclusions: Patients with G2 LC have more recurrences requiring surgery and a higher incidence of TL. Cricoid plate localization is relevant for organ preservation. Margin status signals possible disease persistence, without influencing the need for future surgeries. Need for reoperation entails a risk of not being able to maintain organ functionality.

show abstract

Laryngeal chondrosarcoma – Ten years of experience

Abstract: Laryngeal chondrosarcomas remain a rare disease of unknown etiology, with slow and insidious symptoms. The treatment is surgical, with favorable prognosis, and metastases rarely occur. The main concern regards their propensity to relapse.

Cited by 32 publications

References 10 publications

Chondrosarcoma of the thyroid cartilage: a rare laryngeal malignancy

Chondrosarcoma of the thyroid cartilage: a rare laryngeal malignancy

Laryngeal chondrosarcoma: A systematic review of 592 cases

Organ Preservation Strategies in Laryngeal Chondrosarcoma

Contact Info

Product

Resources

About