Laryngeal chondrosarcoma: A systematic review of 592 cases

Abstract

N/A. Laryngoscope, 2016 127:430-439, 2017.

Chondrosarcoma of the thyroid cartilage: a rare laryngeal malignancy

“…The primary site was most commonly the cricoid in 75% of cases, followed by the thyroid cartilage in 20%, and epiglottis or arytenoids in 5% [1]. Laryngeal chondrosarcomas appear around the age of 60 to 70 years with a clear predominance in males [1][2][3][4][5], as in our patient.…”

“…Our patient presented chronic dysphonia with a hard slowly-growing and painless neck swelling. The very slow evolution of this tumor explains average consultation time of 28 months found in the literature [1,4,6,7].…”

“…It accounts for 0.07 to 2% of laryngeal cancers and less than 1% of all sarcomas [1][2][3][4]. The primary site was most commonly the cricoid in 75% of cases, followed by the thyroid cartilage in 20%, and epiglottis or arytenoids in 5% [1].…”

“…The most likely mechanism would be a primary disorder of cartilage ossification. Some authors suggest chronic inflammation or ischemic changes in a preexisting chondroma [1,4]. Repeated laryngeal trauma, as well as anterior neck irradiation and teflon injection are also implicated [3,4].…”

“…Total laryngectomy is indicated in cases of very advanced lesions, in case of infilration of surrounding tissues, in advanced degree differentiated cancers, or in cases of recurrence [3,4,9]. Lymphnode dissection is not usual, ganglion involvement rarely occurs [6].…”