Is it cost effective to use a 2% chlorhexidine wipes bath to reduce central-line associated blood stream infection? A quasi-experimental study

Feriani, Diego; Souza, E.E. de; Carvalho, Larissa Gordilho Mutti; Ibanês, Aline Santos; Vasconcelos, Eliana; Barbosa, Vera Lúcia; Kondo, Sandra Kiyomi; Abboud, Cely Saad

doi:10.1016/j.bjid.2021.101538

Cited by 3 publications

(2 citation statements)

References 26 publications

(28 reference statements)

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“… 21 In addition, CHG bathing was demonstrated to be economically advantageous. 22 Sandri et al. have described, in nasal carriage of MRSA patients, a significant decrease in the incidence of nosocomial MRSA infection after 2% nasal mupirocin and CHG bathing in an ICU in relation to the pre-intervention period.…”

Section: Introductionmentioning

confidence: 99%

Chlorhexidine gluconate bathing of adult patients in intensive care units in São Paulo, Brazil: Impact on the incidence of healthcare-associated infection

Reis¹,

Almeida²,

Escudero³

et al. 2022

The Brazilian Journal of Infectious Diseases

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Section: Introductionmentioning

confidence: 99%

Chlorhexidine gluconate bathing of adult patients in intensive care units in São Paulo, Brazil: Impact on the incidence of healthcare-associated infection

Reis¹,

Almeida²,

Escudero³

et al. 2022

The Brazilian Journal of Infectious Diseases

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“…(40,41) Ademais, resultados de investigações recentes mostraram que a realização de banho com lenços impregnados em CHG a 2% pode ser uma medida para redução da infecção da corrente sanguínea associada a cateter central. (42,43) Além disso, Reagan et al, demonstrou através da aplicação de um modelo matemático que aumentando a conformidade do banho com CHG na concentração de 2% de 60% para 90%, resultaria na redução de 32% na incidência de IRAS e na economia de aproximadamente US$ 815.000 a cada ano. (44) Contudo, a realização dos banhos com lenços impregnados em CHG a 2% como uma medida de descolonização e prevenção de infecções é um assunto controverso.…”

Section: Definição E Estratégias De Prevenção Das Infecções Primárias...unclassified

Efeitos do banho com lenços impregnados com gluconato de clorexidina entre pacientes críticos para prevenção de infecções da corrente sanguínea associadas a cateter central

Almeida Carvalho Peixoto

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Introduction: Recommendations for different types of bathing to prevent central lineassociated bloodstream infections are still divergent. Purposes: of this study was to verify whether bed bathing with wipes impregnated with 2% chlorhexidine compared to conventional bed bathing is more effective in preventing central line-associated bloodstream infections. Methods: Systematic review of the literature by consulting the electronic databases PubMed/Medline, Embase, CINAHL, Scopus and Web of Science from the date of inception until July 1, 2023, with no language or time restrictions.Randomized controlled trials were evaluated using the tool Risk of Bias Assessment Tool II and the Grading of Recommendations Assessment, Development and Evaluation system. Results: A total of 84,462 studies was examined, of which 6 were included in the meta-analysis. Data from 20,188 critical care patients included in primary studies were analyzed. The meta-analysis found that bed bathing with wipes impregnated with 2% Chlorhexidine reduced the risk of prevent central line-associated bloodstream infections among adult by 48% compared to conventional bed bathing (risk ratio 0.52; 95%CI, 0.37 to 0.73), and this is moderate-quality evidence. The reduction in length of stay in the intensive care unit and length of hospital stay as well as the risk of death were not significantly different between the study groups. Whether bed bathing with 2% Chlorhexidine -impregnated wipes increases the occurrence of skin reactions is unclear. Conclusion:This meta-analysis provides moderate-quality evidence that daily bathing with 2% Chlorhexidine -impregnated wipes is safe and helps prevent central lineassociated bloodstream infections among adult intensive care unit patients.

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Implementing a Compliance Monitoring Process to Promote Chlorhexidine Gluconate Bathing and Hand Hygiene: An Initiative to Decrease Central Line–Associated Bloodstream Infections

Davis,

Wittmann,

Prairie

et al. 2024

Patient Safety

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Background Chlorhexidine gluconate (CHG) bathing has proven to reduce central line–associated bloodstream infections (CLABSI) in hospitalized patients. The aim of this study is to evaluate whether the implementation of a compliance monitoring process for CHG bathing and strict hand hygiene as part of the traditional CLABSI prevention bundle will reduce the overall hospital CLABSI standardized infection ratio (SIR). Methods A quasi-experimental study was conducted in intensive care and non-intensive care inpatient hospital units in an urban 361-bed teaching hospital in Western Pennsylvania. The pre-intervention period consisted of January–August 2021, the intervention period consisted of September–November 2021, and the post-intervention and sustainability period consisted of December 2021–June 2022. A compliance monitoring process for the initiation of a daily bath using a 4% CHG solution and strict hand hygiene surveillance was implemented as part of the standard CLABSI prevention bundle (which includes standardized insertion checklists and processes, daily necessity assessment, dressing change and integrity standards, five moments hand hygiene standards, CHG disk [Biopatch], end caps [Curos], and care of tubing). Outcomes A statistically significant increase in hand hygiene (p=<0.001) and in CHG bathing compliance (p=0.014) helped reduce the overall hospital CLABSI SIR from 1.45 to 0.82, standing for an overall 43.4% decrease. Cost reduction was statistically significant (p=0.011) and was an estimated $1.4 million dollars in savings for the hospital. Next Steps Incorporate the compliance monitoring component for CHG bathing and hand hygiene as part of the best strategy for CLABSI bundle prevention within the healthcare system.

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Is it cost effective to use a 2% chlorhexidine wipes bath to reduce central-line associated blood stream infection? A quasi-experimental study

Cited by 3 publications

References 26 publications

Chlorhexidine gluconate bathing of adult patients in intensive care units in São Paulo, Brazil: Impact on the incidence of healthcare-associated infection

Chlorhexidine gluconate bathing of adult patients in intensive care units in São Paulo, Brazil: Impact on the incidence of healthcare-associated infection

Efeitos do banho com lenços impregnados com gluconato de clorexidina entre pacientes críticos para prevenção de infecções da corrente sanguínea associadas a cateter central

Implementing a Compliance Monitoring Process to Promote Chlorhexidine Gluconate Bathing and Hand Hygiene: An Initiative to Decrease Central Line–Associated Bloodstream Infections

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