Clinical and epidemiological characteristics associated with unfavorable tuberculosis treatment outcomes in TB-HIV co-infected patients in Brazil: a hierarchical polytomous analysis

Prado, Thiago Nascimento do; Rajan, Jayant V.; Miranda, Angélica Espinosa; Dias, Elias dos Santos; Cosme, Lorrayne Beliqui; Possuelo, Lia Gonçalves; Sanchez, Mauro Niskier; Golub, Jonathan E.; Riley, Lee W.; Maciel, Ethel Leonor Nóia

doi:10.1016/j.bjid.2016.11.006

Cited by 34 publications

(35 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The Southeast region accounted for four studies, two in São José do Rio Preto (14)(15) , one in Ribeirão Preto (16) and one in an administrative district of São Paulo (17) . Next, four studies that covered the entire national territory were identified (5,(18)(19)(20) , and finally, two articles in the Northern region, one in the state of Amazonas (21) and one in the capital Manaus (22) . No studies conducted in the Southern and Central-Western regions of Brazil were found.…”

Section: Resultsmentioning

confidence: 99%

“…As for the studies' design, all are observational, and six are of the cross-sectional type (5,17,(19)(20)(21)22) . Five cohort studies (9,10,(12)(13)(14) , three ecological studies (15)(16)18) and one control case (11) were identified.…”

Section: Resultsmentioning

confidence: 99%

“…Studies that met the inclusion criteria = 15 The studies set in Brazil (5,(18)(19)(20) presented a profile with male prevalence; however, one study showed higher incidence of TB/ HIV co-infection in females (19) . Ages ranged from 20 to 60 years old.…”

Section: Studies Identified Via Electronic and Manual Search = 174mentioning

confidence: 99%

See 2 more Smart Citations

Sociodemographic and health profile of TB/HIV co-infection in Brazil: a systematic review

et al. 2019

View full text Add to dashboard Cite

Objective: to ascertain the epidemiological profile of TB/HIV co-infection in Brazilian scenarios. Method: this is a systematic review conducted via electronic search in databases PubMed, EMBASE, LILACS and SciELO, having as inclusion criterion articles based on the Brazilian scenario of TB/HIV co-infection. Results: of the total 174 studies, 15 were selected, revealing the epidemiological profile of the co-infection in different scenarios: male, economically active age, low education level, brown/black ethnicity, low income, heterosexual, pulmonary clinical form, alcoholism and Directly Observed Therapy. Conclusion: the sociodemographic and epidemiological profile of people with TB/HIV co-infection has an expected occurrence pattern, which corroborates articles found in the literature, either at national level or by grouping the studies according to region or state.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Sociodemographic and health profile of TB/HIV co-infection in Brazil: a systematic review

et al. 2019

View full text Add to dashboard Cite

show abstract

“…20 Em pacientes co-infectados, a faixa etária de adulto jovem está associada a maior chance de abandono, enquanto faixas etária igual ou maior a 60 anos a maior chance de óbito; cor negra associada a mais abandono e óbito, assim como alcoolismo. 25,26 Estudo em Zimbabwe sobre mortalidade em tuberculose encontrou maior risco associado a coinfecção pelo HIV e efeito protetor associado ao início de antirretroviral. 24 A coinfecção aumenta a probabilidade de abandono do tratamento, tendo em vista a associação de ambos os tratamentos.…”

Section: Fatores Associados Ao óBito E Ao Abandono Do Tratamento Da Tunclassified

Fatores associados ao desfecho desfavorável do tratamento da tuberculose em um hospital geral do município do Rio de Janeiro, 2007 a 2014

Pereira

Escosteguy

Gonçalves

et al. 2018

Rev Epidemiol Control Infect

View full text Add to dashboard Cite

Exceto onde especificado diferentemente, a matéria publicada neste periódico é licenciada sob forma de uma licença Creative Commons -Atribuição 4. estudo observacional, analítico, de todos os 670 casos confirmados notificados neste período na base local do Sistema de Informação de Agravos de Notificação (SINAN), com encerramento registrado como cura (383), óbito por tuberculose (159) ou abandono do tratamento (128). Este sistema é alimentado a partir de ficha de investigação epidemiológica padronizada, contendo variáveis sociodemográficas e clínicas. A análise estatística envolveu variáveis disponíveis no SINAN e considerou desfecho desfavorável aquele composto por óbito ou abandono. Variáveis com razões de chances elevadas na análise bivariada e/ou importância clínica foram consideradas para inclusão em modelo multivariado de regressão logística. Como medida de associação para análise dos fatores associados a desfecho desfavorável versus cura, foram estimadas as razões de chance e seus intervalos de 95% de confiança. Resultados: foram identificados como fatores estatisticamente associados a chance aumentada do desfecho desfavorável idade ≥60 anos, raça/cor não branca, tratamento prévio para tuberculose ou situação de tratamento prévio desconhecida, resultado de anti-HIV positivo, forma pulmonar e sobretudo forma extrapulmonares grave. Conclusão: esses resultados reforçam a necessidade de investir em políticas que garantam o acesso e a adequada assistência aos pacientes, especialmente àqueles com condições que predispõem a não adesão ao tratamento e formas graves. Descritores: Tuberculose. Vigilância Epidemiológica. Resultado de Tratamento. Modelos Logísticos.Background and Objectives: tuberculosis remains a relevant public health problem and the cure of diagnosed cases is a strategy to reduce high morbidity and mortality. The objective of our study is to identify factors associated with death due to tuberculosis and treatment default in patients diagnosed in the HFSE from 2007 to 2014. Methods: we conducted an observational, analytical study of all 670 confirmed cases reported in this period at the local SINAN reporting base, whose outcome was registered as cure (383)

show abstract

“…Twenty-three percent (23%) of the TB patients were co-infected with HIV/AIDS, emphasizing the importance of HIV screening in all TB patients as this co-infection is a major cause of mortality and worsened treatment outcome [14,15].…”

Section: Discussionmentioning

confidence: 99%

Respiratory-Related Medical Admissions in a Tertiary Institution in South-Western Nigeria

Adeoti¹,

Fadare²,

Ajayi³

et al. 2018

J Gen Pract

View full text Add to dashboard Cite

show abstract

Clinical and epidemiological characteristics associated with unfavorable tuberculosis treatment outcomes in TB-HIV co-infected patients in Brazil: a hierarchical polytomous analysis

Cited by 34 publications

References 26 publications

Sociodemographic and health profile of TB/HIV co-infection in Brazil: a systematic review

Sociodemographic and health profile of TB/HIV co-infection in Brazil: a systematic review

Fatores associados ao desfecho desfavorável do tratamento da tuberculose em um hospital geral do município do Rio de Janeiro, 2007 a 2014

Respiratory-Related Medical Admissions in a Tertiary Institution in South-Western Nigeria

Contact Info

Product

Resources

About