Early-onset neonatal sepsis and the implementation of group B streptococcus prophylaxis in a Brazilian maternity hospital: a descriptive study

Freitas, Felipe Teixeira de Mello; Romero, Gustavo Adolfo Sierra

doi:10.1016/j.bjid.2016.09.013

Cited by 15 publications

(14 citation statements)

References 18 publications

(21 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The prevalence of ENS found in this study is similar to the numbers found in a recent North-American study, in which the rate of ENS ranged from 1 to 4/1,000 live births, depending on the region of the USA and the time of assessment. 12 Regarding the prevalence of proven ENS, the observed value of 0.3/1,000 live births was lower than the one found in an extensive epidemiological study from the United Kingdom (0.71/1,000 live births) 13 , as well as the findings in the Brazilian study by Freitas et al (1.7/1,000 live births) 14 . This difference can be explained by the inclusion of infants born at term or later PTNB in this study, whereas the other analyses described the global prevalence of ENS, without distinction between gestational ages, once the prevalence is inversely proportional to this factor.…”

Section: Discussioncontrasting

confidence: 61%

Early neonatal sepsis: prevalence, complications and outcomes in newborns with 35 weeks of gestational age or more

Camargo¹,

Caldas

Marba

2022

Rev. paul. pediatr.

View full text Add to dashboard Cite

Objective: To analyze the incidence, complications, and hospital discharge status in newborns with ≥35 weeks of gestational age with early neonatal sepsis. Methods: This is a cross-sectional, retrospective study. Cases of early-onset sepsis registered from January 2016 to December 2019 in neonates with gestational age of 35 weeks or more were reviewed in a level III neonatal unit. The diagnoses were performed based on the criteria by the Brazilian Health Regulatory Agency (Anvisa), and the episodes were classified according to microbiological classification and site of infection. The following complications were evaluated: shock, coagulation disorders, and sequelae of the central nervous system. The conditions at hospital discharge were also assessed. The collected data were analyzed with the descriptive analysis. Results: In the period, early neonatal sepsis occurred in 46 newborns, corresponding to 1.8% of all newborns admitted to the neonatal unit, with a prevalence of 4/1,000 live births. Culture confirmed sepsis ocurred in three patients (0.3/1,000 live births), with the following agents: S. pneumoniae, S. epidermidis and S. agalactiae. As to site of infection, there were 35 cases of primary bloodstream infection, seven cases of pneumonia and four cases of meningitis. Most patients (78.3%) had at least one risk factor for sepsis, and all were symptomatic at admission. There were no deaths. Complications occurred in 28.2% of the cases, especially shock (10 cases – 21.7%). Conclusions: The prevalence of proven early neonatal sepsis was low. Despite the common occurrence of complications, there were no deaths.

show abstract

Section: Discussioncontrasting

confidence: 61%

Early neonatal sepsis: prevalence, complications and outcomes in newborns with 35 weeks of gestational age or more

Camargo¹,

Caldas

Marba

2022

Rev. paul. pediatr.

View full text Add to dashboard Cite

show abstract

“…La Figura 1 muestra la incidencia global reportada en distintas latitudes comparada con la reportada en nuestro estudio [24][25][26][27][28][29][30][31][32][33][34][35] . La Figura 2 muestra la variación de la incidencia anual en nuestro centro en comparación con E.U.A.…”

Section: Experiencia Clínicaunclassified

“…La edad mediana materna fue de 20 años (rango [16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35]. La mayoría de las mujeres embarazadas eran primigestas y presentaron cinco o más controles prenatales.…”

Section: Factores Maternos Y Estado De Colonizaciónunclassified

See 1 more Smart Citation

Incidencia de sepsis precoz por Streptococcus agalactiae en recién nacidos del Centro Hospitalario Pereira Rossell en el período 2007-2015

Herrera

Murillo

Gesuele

et al. 2018

Rev. chil. infectol.

View full text Add to dashboard Cite

show abstract

“…En los Estados Unidos predominan las cepas de SBG y los microorganismos gramnegativos 13 . Allí, la incidencia de SN temprana está alrededor de 0.3-0.98 por 1000 nacidos vivos 14,15 , con una mortalidad cerca del 24.4% 16 . Actualmente, existe tendencia al aislamiento de Staphylococcus spp.…”

Section: Introductionunclassified

Sepsis neonatal: aspectos fisiopatológicos y biomarcadores

et al. 2019

View full text Add to dashboard Cite

La sepsis neonatal es una causa importante de morbilidad y mortalidad en recién nacidos a nivel mundial. Su diagnóstico es difícil por sus manifestaciones clínicas inespecíficas y la poca disponibilidad de métodos diagnósticos eficientes. En la fisiopatología de la sepsis se ha descrito una respuesta inmune excesiva o suprimida que puede conducir a desenlaces potencialmente fatales. Se ha estudiado la utilidad pronóstica, diagnóstica y de seguimiento de factores solubles que se alteran en la sepsis neonatal y se han agrupado bajo el término biomarcadores de sepsis neonatal. Aquí se describen los principios fisiopatológicos de la sepsis neonatal y las características de los biomarcadores más usados para su diagnóstico, además, se mencionan detalles de otros marcadores que también han sido estudiados recientemente. Actualmente, se recomienda el uso de un biomarcador temprano en combinación con uno tardío para lograr un mejor rendimiento, sin embargo, aún no se ha identificado un biomarcador ideal para la sepsis neonatal. MÉD.UIS.2019;32(3):35-47

show abstract

Early-onset neonatal sepsis and the implementation of group B streptococcus prophylaxis in a Brazilian maternity hospital: a descriptive study

Abstract: Although the reduction of EOS incidence was not significant, GBS colonization among pregnant women was high, no cases of neonatal GBS have occurred after implementation of prevention guidelines.

Cited by 15 publications

References 18 publications

Early neonatal sepsis: prevalence, complications and outcomes in newborns with 35 weeks of gestational age or more

Early neonatal sepsis: prevalence, complications and outcomes in newborns with 35 weeks of gestational age or more

Incidencia de sepsis precoz por Streptococcus agalactiae en recién nacidos del Centro Hospitalario Pereira Rossell en el período 2007-2015

Sepsis neonatal: aspectos fisiopatológicos y biomarcadores

Contact Info

Product

Resources

About