Oral health-related quality of life of children and teens with sickle cell disease

Abstract

BackgroundChildren with sickle cell disease may have their quality of life affected by oral alterations. However, there is still little data on oral health-related quality of life in these children. The aim of this study was to investigate the influence of sickle cell disease, socioeconomic characteristics, and oral conditions on oral health-related quality of life of children and teens.MethodOne hundred and six children and teens with sickle cell disease were compared to a similar sample of 385 healthy peers. Data were collected through oral examinations, interviews to assess quality of life (Child Perceptions Questionnaire for children aged 8–10 and 11–14) and questionnaires containing questions on socioeconomic status.ResultsThere were no statistically significant differences in the total scores of the Child Perceptions Questionnaires or domain scores comparing sickle cell disease patients to control subjects. When sub-scales were compared, oral symptoms and functional limitations had a greater negative impact on the quality of life of adolescents with sickle cell disease (p-value <0.001 and p-value <0.01, respectively) when compared to healthy controls. The only statistically significant determinants of negative impact on oral health-related quality of life in the overall sample was home overcrowding (more than two people/room) in the younger children's group, and dental malocclusion among teens.ConclusionThere was no significant difference in the negative impact on the oral health-related quality of life between the group with sickle cell disease and the control group. Of the oral alterations, there was a significant difference in the oral health-related quality of life between adolescents with sickle cell disease and controls only in relation to malocclusion. Among the socioeconomic characteristics, only overcrowding was significantly associated with a negative impact on oral health-related quality of life.

Oral health status and treatment needs of children with sickle cell disease in Abha and Khamis Mushait cities of southern Saudi Arabia

“…17 In our study, the experience of dental caries among children with SCD and their peer (without SCD), was similar to the experience observed by Maria et al, they found that children with SCD has less prevalence of dental caries. 18 The results reinforce the importance of care related to oral health among children and emphasize the need to implement appropriate preventive measures for these patients taking into account factors that were associated with caries. A study was conducted by Okafor et al, prevalence of dental caries was higher in subjects without SCA (54%) as compared with those with SCA (35.13%).…”

Health-related quality of life in children and adolescents with sickle cell disease

“…As patients with SCD are at a greater risk for severe comorbidities associated with vascular occlusion, hemolysis, and infection, in addition to oral disorders, their quality of life could be compromised (Fernandes et al, 2016). Hemoglobinopathies are often severe, present difficult management, and have a remarkable psychosocial impact on patients and on their families (Dahmani et al, 2017).…”

Oral health-related quality of life in children and adolescents with osteogenesis imperfecta: cross-sectional study

“…The overall CPQ scores are computed by adding up all four domain subscale scores, which may range from 0 to 100 for CPQ 8–10 and 0 to 148 for CPQ 11–14 . Higher scores denote worse OHRQoL [ 12 – 14 , 16 ]. The validity, reliability, and responsiveness of this measure have been established in various settings [ 17 – 22 ].…”