Effects of music therapy on pain and oxidative stress in oocyte pick-up: A randomized clinical trial

Effectiveness of music therapy as an adjuvant to conscious sedation in women undergoing transvaginal oocyte retrieval: A randomized controlled trial

“…The study further reported that the need for additional analgesia in terms of diclofenac and remifentanil was significantly lower in the intervention group. Hemodynamic markers such as mean arterial pressure and pulse rate were found to be significantly higher in the group offered music therapy 22 . The findings of the study are contradictory to the current study.…”

“…Another RCT conducted among Turkish women ( n = 93) compared the effects of local music on women undergoing transvaginal oocyte retrieval in terms of difference in pain perception, biochemical markers of stress (N‐methyl D‐aspartate [NMDA], nitric oxide [NO]) and changes in hemodynamic parameters such as mean arterial pressure and heart rate 22 . The authors reported a significant decrease in postoperative pain (as evaluated using the VAS‐P scale) at 1st, 5th, and 60th min postprocedure in women who were randomized to music arm versus the control 22 . Additionally, markers of stress (NMDA and NO) were also found to be significantly lower in women who heard music during the procedure.…”

“…A randomized controlled trial (RCT) comprising 93 Turkish women reported significant improvement in pain and anxiety levels during oocyte retrieval in women who were offered music therapy. 22 Another similar trial conducted in China with 209 infertile women reported that there was no beneficial effect of music therapy during oocyte retrieval, with comparable pain and anxiety scores in both study groups. 23 Due to the paucity of evidence on the effectiveness of music therapy for pain relief during oocyte retrieval we planned to assess whether music therapy could be used as an effective adjuvant to conscious sedation for relieving pain and anxiety during transvaginal oocyte retrieval.…”

“…There are only two published trials that have evaluated effectiveness of pain relief with music therapy during oocyte retrieval. A randomized controlled trial (RCT) comprising 93 Turkish women reported significant improvement in pain and anxiety levels during oocyte retrieval in women who were offered music therapy 22 . Another similar trial conducted in China with 209 infertile women reported that there was no beneficial effect of music therapy during oocyte retrieval, with comparable pain and anxiety scores in both study groups 23 .…”

The Therapeutic Effect of Music on Oxidative Stress Markers and Anxiety in Hypertension

“…The results of the present study are in good agreement with a randomized control trial by Orak et al, and they demonstrated a favourable result on oxidative stress with Turkish classical music in individuals undergoing oocyte pick-up [42] 489 An animal study used a combination of Mozart classical music and cocoa powder and found out a significant improvement in the antioxidant activity [43] 490 Music moderated the oxidative stress in hypertensive patients as marked by the results of the present study and the above observation may be due to the overall improvement in the anxiety level and blood pressure with music intervention. Hence, these parameters can influence the body's antioxidant status and oxidative stress.…”