Effectiveness of ozone therapy compared to other therapies for low back pain: a systematic review with meta-analysis of randomized clinical trials

Andrade, Raul Ribeiro de; Oliveira-Neto, Olavo Barbosa de; Barbosa, Luciano Timbó; Santos, Isabelle Oliveira; Sousa‐Rodrigues, Célio Fernando de; Barbosa, Fabiano Timbó

doi:10.1016/j.bjane.2019.06.007

Cited by 7 publications

(15 citation statements)

References 17 publications

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“…There are various applications of ozone in medicine, such as oxygen-ozone injection in cases of herniated discs (de Andrade et al 2019;Lehnert et al 2012;Zhang et al 2013) or knee osteoarthritis (Borrelli et al 2015;Hashemi et al 2015). In addition, ozonated water is utilized to treat avulsed teeth in dentistry (Azarpazhooh and Limeback 2008;Zimmermann, Waltimo, and Filippi 2012).…”

Section: Introductionmentioning

confidence: 99%

Development of an Experimental Setup for Real-Time In-Line Dissolved Ozone Measurement for Medical Therapy

Petani

Wührl

Koker

et al. 2021

Ozone: Science & Engineering

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Ozone therapy is established in clinical applications since many decades, such as treatment of infections or herniated discs. However, in-line monitoring of ozone concentrations is challenging and therefore not performed by default. We developed an experimental setup to measure the inline ozone concentration in water in real-time with a spectroscopic sensor. Thereby, the experimental setup enables the calibration and evaluation of newly evolved ozone sensors. The results for ozone concentration measurement with the spectroscopic sensor and the colorimetric photometer show a very good correlation. Furthermore, the ozone decay curves measured with our experimental setup highly correlate with those of previous research.

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Section: Introductionmentioning

confidence: 99%

Development of an Experimental Setup for Real-Time In-Line Dissolved Ozone Measurement for Medical Therapy

Petani

Wührl

Koker

et al. 2021

Ozone: Science & Engineering

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“…Conventional treatment of pain caused by a herniated disk or osteoarthritis of the joints consists of repeated injections of anti-inflammatory drugs-such as corticosteroids, immunosuppressive drugs, and antibiotics [5,6]. These drugs are only partially and transiently effective.…”

Section: Introductionmentioning

confidence: 99%

“…For example, subcutaneous carbon dioxide is utilised to relieve muscle pain and nitrous oxide is applied as an anaesthetic in obstetrics and during prostrate examinations [7,8]. Furthermore, there are other gases with therapeutical potential, such as ozone [5,[9][10][11][12][13][14] and xenon [15]. However, for xenon further research in clinical studies is necessary to prove its therapeutic effectiveness [15].…”

Section: Introductionmentioning

confidence: 99%

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Recent Developments in Ozone Sensor Technology for Medical Applications

et al. 2020

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There is increasing interest in the utilisation of medical gases, such as ozone, for the treatment of herniated disks, peripheral artery diseases, and chronic wounds, and for dentistry. Currently, the in situ measurement of the dissolved ozone concentration during the medical procedures in human bodily liquids and tissues is not possible. Further research is necessary to enable the integration of ozone sensors in medical and bioanalytical devices. In the present review, we report selected recent developments in ozone sensor technology (2016–2020). The sensors are subdivided into ozone gas sensors and dissolved ozone sensors. The focus thereby lies upon amperometric and impedimetric as well as optical measurement methods. The progress made in various areas—such as measurement temperature, measurement range, response time, and recovery time—is presented. As inkjet-printing is a new promising technology for embedding sensors in medical and bioanalytical devices, the present review includes a brief overview of the current approaches of inkjet-printed ozone sensors.

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“…Most recently reports from China, Italy, Spain and South America report the benefi cial use of ozone therapy in extremely ill patients with associated acute respiratory insuffi ciency [1][2][3][4][5][6][7][8]. Despite the extensive use of ozone among Integrative / Wellness providers in the US and world wide there are very few prospective studies [9][10][11]. There are multiple proposed mechanisms by Citation: Thorp JA, Hollonbeck SA, Viglione DD, Green PC, Hodge JR, et al (2020) Novel therapy for COVID-19 does intravenous ozonated-saline affect blood and tissue oxygenation?…”

Section: Introductionmentioning

confidence: 99%

Novel therapy for COVID-19 does intravenous ozonated-saline affect blood and tissue oxygenation?

Ja¹,

Sa²,

Dd³

et al. 2020

J Gynecol Res Obstet

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which adjuvant ozone therapy for COVID-19 could possibly improve outcomes: 1) Ozone is virucidal; 2) Ozone increases oxygenation of blood and tissues; 3) Ozone stimulates immune function via nuclear factor erythroid 2-related factor 2 (NRF2); 4) Ozone inhibits infl ammatory mediators (interleukins, cytokines, and tumor necrosis factors; 5) Ozone activates endogenous antioxidant immune defenses; 6) Ozone inhibits viral replication; 7) Ozone inhibits micro thrombus formation; 8) Ozone up-regulates HO-1 in endothelial cells and; 9) Ozone stimulates the 2-3 diphosphoglycerate that shifts the oxygen

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Effectiveness of ozone therapy compared to other therapies for low back pain: a systematic review with meta-analysis of randomized clinical trials

Cited by 7 publications

References 17 publications

Development of an Experimental Setup for Real-Time In-Line Dissolved Ozone Measurement for Medical Therapy

Development of an Experimental Setup for Real-Time In-Line Dissolved Ozone Measurement for Medical Therapy

Recent Developments in Ozone Sensor Technology for Medical Applications

Novel therapy for COVID-19 does intravenous ozonated-saline affect blood and tissue oxygenation?

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