Correlation of computed tomography, magnetic resonance imaging and clinical outcome in acute carbon monoxide poisoning

Özcan, Namık; Ozcam, Giray; Koşar, Pınar Nercis; Özcan, Ayşe; Başar, Hülya; Kaymak, Çetin

doi:10.1016/j.bjane.2014.05.006

Cited by 5 publications

(7 citation statements)

References 9 publications

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“…23 There are only case reports on the diagnostic usefulness of DWI, which can detect early changes in ischemic tissues and is sensitive to cytotoxic or vasogenic edema, 21,22 in the acute phase of CO exposure. 12,24,25 No previous study has determined whether early use of DWI can predict which patients will develop DNS in the acute CO poisoning.…”

Section: Introductionmentioning

confidence: 99%

The usefulness of diffusion-weighted magnetic resonance imaging performed in the acute phase as an early predictor of delayed neuropsychiatric sequelae in acute carbon monoxide poisoning

et al. 2017

Hum Exp Toxicol

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Delayed onset of neuropsychiatric symptoms after apparent recovery from acute carbon monoxide (CO) poisoning has been described as delayed neuropsychiatric sequelae (DNS). No previous study has determined whether early use of diffusion-weighted magnetic resonance imaging (DWI) can predict which patients will develop DNS in the acute CO poisoning. This retrospective observational study was performed on adult patients with acute CO poisoning consecutively treated over a 17-month period. All included patients with acute CO poisoning underwent DWI to evaluate brain injury within 72 h after CO exposure. DWI was evaluated as follows: (1) presence of pathology, (2) number of pathologies, (3) asymmetry, and (4) location of pathology. Patients were divided into two groups. The DNS group was composed of patients with delayed sequelae, while the non-DNS group included patients with no sequelae. A total of 102 patients with acute CO poisoning were finally enrolled in this study. DNS developed in 10 patients (9.8%). Between the DNS group and the non-DNS group, presence of pathology on DWI and initial Glasgow Coma Scale (GCS) showed significant difference. There was also a statistical difference between the non-DNS group and DNS group in terms of CO exposure time, troponin I, rhabdomyolysis, acute kidney injury, and pneumonia. The presence of pathology in DWI and initial GCS (cutoff: <12) at the emergency department served as an early predictors of DNS.

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Section: Introductionmentioning

confidence: 99%

The usefulness of diffusion-weighted magnetic resonance imaging performed in the acute phase as an early predictor of delayed neuropsychiatric sequelae in acute carbon monoxide poisoning

et al. 2017

Hum Exp Toxicol

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“…If undetected, CO poisoning may affect white matter severely, including demyelination, leading to loss of vision, speech impairment, and physical disability [25]. Demyelination is believed to result from delayed encephalopathy [22].…”

Section: White Mattermentioning

confidence: 99%

“…Devine, et al [23], argued that demyelination of white matter is often more reversible than lesions of the globus pallidus. Ozcan, et al [25], argued that demyelination reaching the white matter is found only in severe cases.…”

Section: White Mattermentioning

confidence: 99%

“…The authors concluded that the different outcomes were influenced by several factors, including the length of hypoxic exposure, individual responses to white matter hypoxic injury, and even genetics [20]. Ozcan, et al [25], Raub, et al [26], and Yoshiike, et al [17], also reported cases of patients suffering from white matter lesions caused by CO poisoning in which long-term cognitive deficiencies resulted. Murata, et al [27], discussed a patient with white matter lesions who suffered neuronal necrosis progressing from demyelinating membrane destruction.…”

Section: White Mattermentioning

confidence: 99%

“…Among the cases analyzed for this review, two patients who suffered damage to the globus pallidus made full recoveries [18,25]. Only one case, presented in Baud, et al [32], died.…”

Section: Globus Pallidusmentioning

confidence: 99%

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2021

IJHMS

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Carbon monoxide (CO) poisoning is a major public health issue in the United States that accounts for approximately 50% of poisoning cases in the nation each year and around 50,000 emergency room visits. In most instances of CO poisoning, the culprit is a malfunctioning or poorly tended heating system within the home or, occasionally, commercial building, which causes the system to leak this hazardous gas. One of the more insidious aspects of CO poisoning is that the gas is odorless and colorless, and victims of CO poisoning often do not realize that there is a problem until they begin to experience the effects of poisoning and have no choice but to seek medical attention. Unfortunately, many victims of CO poisoning die before they are able to seek treatment. This paper makes use of a qualitative, systematic literature review to examine the four major parts of the brain that are most severely affected by CO poisoning. Overall, the literature review showed that the white matter, globus pallidus, basal ganglia, and cortex are the parts of the brain most severely impacted by CO poisoning. While many CO poisoning victims do make it to the hospital on time and are treated, they may nonetheless suffer long-term neurological consequences as a result of their exposure. As such, CO poisoning is a major public health issue.

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Carbon monoxide-triggered health effects: the important role of the inflammasome and its possible crosstalk with autophagy and exosomes

et al. 2021

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Correlation of computed tomography, magnetic resonance imaging and clinical outcome in acute carbon monoxide poisoning

Abstract: White matter lesions which progress to demyelination and end up in neuropsychological sequelae cannot always be diagnosed by early computed tomography and magnetic resonance imaging in carbon monoxide poisoning.

Cited by 5 publications

References 9 publications

The usefulness of diffusion-weighted magnetic resonance imaging performed in the acute phase as an early predictor of delayed neuropsychiatric sequelae in acute carbon monoxide poisoning

The usefulness of diffusion-weighted magnetic resonance imaging performed in the acute phase as an early predictor of delayed neuropsychiatric sequelae in acute carbon monoxide poisoning

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Carbon monoxide-triggered health effects: the important role of the inflammasome and its possible crosstalk with autophagy and exosomes

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