Pediatric androgenetic alopecia: a retrospective review of clinical characteristics, hormonal assays and metabolic syndrome risk factors in 23 patients

Özcan, Deren

doi:10.1016/j.abd.2021.06.006

Cited by 6 publications

(37 citation statements)

References 19 publications

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“…In a cohort of 43 adolescents reported by Kim et al., only one 18‐year‐old girl presented increased serum hormone levels but with normal physical development and growth 5 . A study by Ozcan with 23 patients with adolescent AGA found elevated levels of free and total testosterone in two patients (1 female and 1 male) and elevated androstenedione in one female 3 . Gonzalez et al.…”

Section: Work‐upmentioning

confidence: 93%

“…15 In AGA, trichoscopy reveals > 20% of thin hairs (hair diameter variability known as anisotrichia) as a consequence of miniaturization, and an increase in the number of follicular units with a single hair shaft (Figure 1). 3,12,13 Yellow dots, perifollicular discoloration and higher proportion of vellus hairs may also be present in the trichoscopic examination. 16 Trichoscopy will be conclusive in most of the cases.…”

Section: Diagnosismentioning

confidence: 99%

“…Pediatric AGA can be classified according to the stage of development of the child in prepubertal (childhood) and postpubertal (adolescent) AGA 3 . Thus, the presence of breast development, pubic and axillary hair and menstruation at the time of onset of the hair loss should be evaluated 3 . Some authors consider the age of 12 as the cut‐off to the beginning of adolescence, when it is not possible to determine pubertal timing 2 …”

Section: Epidemiologymentioning

confidence: 99%

See 2 more Smart Citations

Pediatric androgenetic alopecia: an updated review

Gomes

Soares

2023

J Deutsche Derma Gesell

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Summary Pediatric androgenetic alopecia is an underrecognized disorder. A clinical evaluation with trichoscopy should be made in children and adolescents with hair loss and/or reduced hair density. Diagnosis is usually clinical, by observation of the hair loss pattern and performance of trichoscopy. In some cases, hyperandrogenism should be excluded. Although there is no approved therapy for androgenetic alopecia in pediatric age, topical minoxidil, oral minoxidil and topical finasteride may be very useful. Hair transplant may be an option for girls in selected cases. This article is a review of the current state of evidence concerning pediatric androgenetic alopecia.

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Section: Work‐upmentioning

confidence: 93%

Section: Diagnosismentioning

confidence: 99%

Section: Epidemiologymentioning

confidence: 99%

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Pediatric androgenetic alopecia: an updated review

Gomes

Soares

2023

J Deutsche Derma Gesell

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“…Pädiatrische AGA kann entsprechend dem Entwicklungsstadium des Kindes in präpubertär (Kindheit) und postpubertär (Jugendalter) eingeteilt werden 3 . Daher sollten bei Beginn des Haarausfalls auch die Entwicklung der Brust, das Scham‐ und Achselhaar sowie die Menstruation beurteilt werden 3 .…”

Section: Epidemiologieunclassified

“…Das Alter zu Beginn der Krankheit ist bei weiblichen Patienten etwas niedriger 2,4,5 . In einigen Kohorten überwiegen die Männer, 2,5 in anderen hingegen sind Frauen am häufigsten betroffen 3,4 …”

Section: Epidemiologieunclassified

Aktuelle Übersicht zur androgenetischen Alopezie bei Kindern und Jugendlichen

Gomes

Soares

2023

J Deutsche Derma Gesell

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Pädiatrische androgenetische Alopezie ist eine zu wenig beachtete Erkrankung. Bei Kindern und Jugendlichen mit Haarausfall und/oder verminderter Haardichte sollte eine klinische Beurteilung mittels Trichoskopie vorgenommen werden. Die Diagnose wird in der Regel klinisch, durch Beobachtung des Haarausfallmusters und Trichoskopie gestellt. In einigen Fällen sollte eine Hyperandrogenämie ausgeschlossen werden. Es gibt zwar keine zugelassene Therapie für androgenetische Alopezie im Kindesalter, topisches Minoxidil, orales Minoxidil und topisches Finasterid können jedoch helfen. Eine Haartransplantation könnte für Mädchen in ausgewählten Fällen eine Option sein. Dieser Artikel gibt einen Überblick über den aktuellen Stand der Erkenntnisse zur pädiatrischen androgenetischen Alopezie.

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Androgenetic Alopecia in Children and Adolescents: From Trichoscopy to Therapy

Losoya-Jaquez,

Lopez Yañez-Blanco,

Armendariz-Barragan

et al. 2023

Skin Appendage Disord

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Introduction: Pediatric androgenetic alopecia is a product of hormonal and genetic factors. The diagnosis depends on recognizing the hair loss pattern in the context of a positive family history and a typical trichoscopy. Methods: A multicenter retrospective study assessing medical data from January 2008 to January 2023 of two reference centers – one public and one private in west Mexico. Patients under 18 years old were included. The clinical features, trichoscopic findings, associated conditions, and treatment received were documented and analyzed. Results: We found 145 patients, with a mean age of 16.08 ± 1.30 years, predominantly comprising males (72%). Trichoscopy was performed on 33 patients. The main trichoscopic findings were hair shaft thickness variability in 100% of the cases, vellus hair in 85%, and single-hair units in 79%. Vitamin D deficiency was found in 84% of the cases with laboratory determination, insulin resistance in 33%, and hyperandrogenemia in 12.5%. Topical minoxidil emerged as the main treatment modality in 24% of cases, demonstrating both efficacy and tolerability. Conclusion: Pediatric androgenetic alopecia could be more prevalent than commonly perceived, potentially explained by the lower level of suspicion among medical practitioners. Distinctive trichoscopic findings offer valuable guidance for therapeutic strategies and ongoing management.

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Pediatric androgenetic alopecia: a retrospective review of clinical characteristics, hormonal assays and metabolic syndrome risk factors in 23 patients

Cited by 6 publications

References 19 publications

Pediatric androgenetic alopecia: an updated review

Pediatric androgenetic alopecia: an updated review

Aktuelle Übersicht zur androgenetischen Alopezie bei Kindern und Jugendlichen

Androgenetic Alopecia in Children and Adolescents: From Trichoscopy to Therapy

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