Demodex folliculorum infestations in common facial dermatoses: acne vulgaris, rosacea, seborrheic dermatitis

Karabay, Ezgi Aktaş; Çerman, Aslı Aksu

doi:10.1016/j.abd.2019.08.023

Cited by 65 publications

(87 citation statements)

References 42 publications

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“…Demodex sp. infestation is associated with acne vulgaris, rosacea, and seborrheic dermatitis [ 8 ]. Ophthalmic demodicosis manifests as persistent blepharitis [ 9 ], chalazion, and dry eye syndrome [ 10 ] or may be associated with eyelid basal cell carcinoma [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Ocular Demodicosis and Ocular Surface Conditions in Patients Selected for Cataract Surgery

Nowomiejska

Łukasik

Brzozowska

et al. 2020

JCM

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The aim of the study was to analyze the prevalence of ocular demodicosis and ocular surface conditions in patients selected for cataract surgery. Eyelashes from 73 patients selected for cataract surgery were evaluated at × 40 and × 100 magnification using light microscopy. The anterior segment was assessed with the slit lamp. Additionally, Schirmer I and break up time (BUT) tests were carried out before surgery and 1 and 3 months postoperatively. A specially designed questionnaire containing e.g. information about chronic skin and eye diseases, previous ophthalmic surgeries, and patient's hygiene habits was used to assess the demographic variables. A majority of patients were at the age of 70–79 years, and there were more females (83%) in the study group. Demodex folliculorum was found in 48% of the patients. There was a correlation between the number of parasites and the presence of blepharitis, discharge at eyelid margins, and conjunctival hyperemia. Schirmer I and BUT test results were lower in patients with Demodex infestation before and after cataract surgery. The higher number of mites was correlated with lower Schirmer I test results postoperatively. The presence of Demodex mites influences the conjunctiva and lid margins leading to inflammation. The higher number of Demodex mites disturbs the tear film over time after cataract surgery.

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Section: Introductionmentioning

confidence: 99%

Prevalence of Ocular Demodicosis and Ocular Surface Conditions in Patients Selected for Cataract Surgery

Nowomiejska

Łukasik

Brzozowska

et al. 2020

JCM

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“…Most people serving as a host for these mites rarely present clinical symptoms 1,2 . Infestation of Demodex folliculorum mite is also found in patients with rosacea, acne vulgaris, and blepharitis 3 . D folliculorum infestation is frequently found in chronic renal failure, diabetes, HIV infections, and in patients receiving immunosuppressive drugs 4,5 .…”

Section: Introductionmentioning

confidence: 99%

Association between Demodex folliculorum and Metabolic Syndrome

Özer¹,

Akyürek

Durmaz³

2020

J of Cosmetic Dermatology

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Background Demodex folliculorum mite infestation is associated with many diseases such as rosacea, pityriasis found with acne vulgaris, and blepharitis. Aim In this research, the aim of this study was to investigate an association between patients who have metabolic syndrome and presence of Demodex folliculorum. Patients/Methods This research was planned prospectively as a case‐control study. Fifty cases who have metabolic syndrome and 50 control subjects in good health were included. Metabolic syndrome was diagnosed according to the NCEP Adult Treatment Panel III criteria. Standard superficial skin biopsy was performed for the presence of Demodex folliculorum mite infestation. Results It was detected that number of Demodex affected from the glucose level and each increase in glucose level cause an increase on Demodex as 0.190 (P = .00, t = 4.746, B = 0.190, r = 0.57, Durbin‐Watson = 1.801, confidence interval = 0.110 to 0.271 (for glucose)). Conclusion In this study, the presence of Demodex folliculorum was found to be higher in the cases who have metabolic syndrome compared to the healthy group. These results show that in cases with metabolic syndrome, high blood sugar levels make them more susceptible to infestation of Demodex folliculorum.

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“…parasitic diseases [2,4,7,15,16,20,21]. Considering that data on the shortcomings of traditional confirmatory methods of parasitic skin diseases (PSD) are increasingly appearing in the literature, new developing diagnostic possibilities have been studied [1,2,18]. Moreover, many advanced and noninvasive techniques such as videodermatoscopy, dermatoscopy, in vivo reflectance confocal microscopy, and optical coherence tomography have demonstrated improved efficacy in the diagnostics of parasitic skin infections [7,18,20,23].…”

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confidence: 99%

“…Moreover, many advanced and noninvasive techniques such as videodermatoscopy, dermatoscopy, in vivo reflectance confocal microscopy, and optical coherence tomography have demonstrated improved efficacy in the diagnostics of parasitic skin infections [7,18,20,23]. According to Aktaş Karabay E. et al (2020) [1], who aimed at detecting Demodex infestation (DI) due to observational case-control study of 127 patients (43 with acne vulgaris, 43 with rosacea and 41 with seborrheic dermatitis) and 77 healthy controls, some limitations of the study were revealed: the lack of an objective scoring system in Demodecosis diagnosis which limits making comments on the association between the severity of the infestation and dermatoses and small sample size is a is another limitation. Furthermore, facial dermatosis, such as.…”

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confidence: 99%