?1-Piperidein-6-carhons�ure, ein enzymatisches Reaktionsprodukt

The Preparation and Some Properties of α-Aminoadipic-δ-Semialdehyde (Δ1-Piperideine-6-carboxylic Acid)*

“…Evidence for the enzymatic formation of aaminoadipic-6-semialdehyde from a-amino-e-hydroxycaproic acid catalyzed by a pyridine nucleotide-dependent enzyme from Neurospora crassa that also catalyzes the reversible formation of glutamic --semialdehyde from aamino -hydroxyvaleric acid has been reported by Yura and Vogel (1959). Hasse et al (1961) have also observed this reaction and have reported that the oxidation of lysine by pea seedling diamine oxidase yields a-aminoadipic-ó-semialdehyde; identification was based on comparisons of the electrophoretic and chromatographic properties of the product (and of its o-aminobenzaldehyde derivative) with those of an a-aminoadipic-d-semialdehyde preparation obtained by chromic acid oxidation of a-aminoe-hydroxycaproic acid (Hasse and Wieland, 1960).…”