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Abstract

Plant mucilages have found wide application in food, pharmaceutical and cosmetic industries. Hence, it would be worthwhile to characterise the physical and chemical attributes of mucilages from commonly available plants for their beneficial utilization. Hibiscus rosasinensis Linn. (Family Malvaceae), widely grown as an ornamental throughout the tropics and subtropicsis a good source of mucilage. The present study focuses on the extraction of the mucilage from the leaves of Hibiscus rosa-sinensis, its subsequent quantification and physico-chemical characterisation. A protocol was presently standardized for the yield optimization of mucilage from Hibiscus through detection of an appropriate maceration temperature and precipitation solvent. Further analyses revealed ideal pH value, swelling index, flow properties and particle size of Hibiscus mucilage. Moreover, chemical, FTIR spectral and electrokinetic data of Hibiscus mucilage revealed that it can be considered as a suitable blending ingredient in composites with potential industrial applications. INTRODUCTION: Mucilages are normal metabolic products formed from sugars and uronic acid units in plant cells. Hydrophilic nature of mucilagenous plant parts becomes evident from the viscous and slimy mass it forms when dissolved in water 1. Some of the mucilage rich plants are Aloe vera, Abelmoschus esculentus, Trigonella foenumgraceum, Asparagus racemosus, Lepidium sativum, Salvia hispanica, Althaea officinalis and Hibiscus rosa-sinensis 2, 3. Generally, mucilages are merely considered as carbohydrate reserves in plant cells. However, reports show that they provide additional physiological benefits to plants including frost tolerance, water transport, wound response, plant host-pathogen interaction and maintenance of ionic balance of plant cells 4, 5 .

In-vitro ANTI-INFLAMMATORY AND ANTI-ARTHRITIC ACTIVITY OF ETHANOLIC EXTRACT OF Hibiscus rosa sinensis LEAVES

“…The hemolysis of membrane is reduced with increasing concentrations, as shown in At various concentrations, the ethanolic extract of Hibiscus showed substantial activity and its effect was contrasted with standard drug. 89.45% and 91.09% were found to be the highest percent inhibition of denaturation of protein [15][16] and membrane stabilization at 500μg/ml as shown in Table-3. Auto antigen productions are formed in some arthritic disorders due to denaturation of protein and membrane lysis.…”

Hibiscus Rosa-Sinensis Mucilage as a Functional Polymer in Pharmaceutical Applications: A Review

“…HRS mucilage extract is a greenish-brown powder with a characteristic odour and amorphous nature. When dissolved in water, it provides a neutral, greenish-brown solution that is slimy and colloidal [17].…”

“…HRS mucilage is soluble in water but insoluble in methanol, ethanol, acetone and chloroform [17,18]. The pH of HRS mucilage is generally 6.2, which is nearly neutral [17,18,20] and therefore will not irritate the mucosal membranes of the body.…”

“…HRS mucilage is soluble in water but insoluble in methanol, ethanol, acetone and chloroform [17,18]. The pH of HRS mucilage is generally 6.2, which is nearly neutral [17,18,20] and therefore will not irritate the mucosal membranes of the body. Drug-excipient compatibility studies have shown no significant interactions [6,[21][22][23], indicating that HRS mucilage can be used for a wide range of drugs.…”

“…HRS is the most common species used in medicines. The presence of mucilage is typical in the Malvaceae, and its extraction is carried out from the leaves and flowers [17]. This article discusses the use of HRS mucilage in a variety of pharmaceutical dosage forms to improve drug delivery.…”