Xanthogranulomatous inflammation is a rare inflammatory reaction, characterized by lipid-laden macrophages, known as xanthomas, in histopathologic examination. Aggressive xanthogranulomatous inflammation often manifests as local infiltration but does not affect distant organs unless combined with rare systemic diseases. We report a case of focal xanthogranulomatous pyelonephritis (XGP) associated with severe xanthogranulomatous cholecystitis. Focal XGP was suspected in radiologic examination that showed a cystic lesion with an infiltrative margin, which were surgically resected and confirmed in pathologic examination. To our knowledge, this is the first report of focal xanthogranulomatous pyelonephritis associated with xanthogranulomatous cholecystitis. Moreover, we found peripheral hypointensity around the cystic lesion in the T2-weighted image, probably reflecting hemorrhage and fibrosis of the xanthogranulomatous inflammation.
The aim of this study is to produce standardized statistics about stroke in Korea and to provide a high-quality standardized management system. This study was conducted with two sub-studies. The first sub-study had the purpose of registration of stroke patients to a structured cohort (Clinical Research Collaboration for Stroke-Korea-National Institute of Health) and longterm follow-up. The second sub-study was directed to organize, operate, and manage the Korea Stroke Registry. During the 5-year of the study period, 25,515 patients from 17 hospitals were enrolled in the cohort, and blood samples from 360 patients with arterial dissection and transient ischemic attack were deposited with the National Human Resources Bank. In addition, a 3-year long-term follow-up cohort was prepared. Korean Stroke Registry started with 43 hospitals and expanded with more than 25 centers expected to be participating, and a total of 66,701 patients from 55 hospitals were registered. Promotions for enrolling more hospitals, and establishing multiple patient data input systems, open proposal systems, and Korea stroke registry core database quality improvement systems were done. In addition, the annual report on Korean stroke registration was published. Through this study, we laid the basis for further stroke-related research by establishing acute stroke cohort and registry. It is hoped that this cohort and registry would be useful in the process of obtaining national statistics on stroke, which will eventually serve as the basis for policy research to build a "Stroke safety net".
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