This study was done to identify the mediating effect of resilience on the relationship between nurse's character and happiness for nurses in general hospitals. Methods: Participants were 139 nurses working in general hospitals. A survey was used and data were collected in April 2019. Data were analyzed using the IBM SPSS/WIN 22.0 program. Results: The significant predictors for the happiness of nurses were nurse's character (β=.56) and resilience (β=.80). These variables explained 67% of the variance in happiness of nurses. Also, resilience had a total mediating effect on the relationship between nurse's character and happiness. Conclusion: Findings indicate that nurse's character and resilience are important factors for the happiness of nurses in general hospitals.
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