The present study aimed to evaluate the in vitro antimycobacterial effects of hop plant, Humulus japonicus. Methanol extract of H. japonicus (MeOH extract) showed strong direct bactericidal effects against Mycobacterium tuberculosis in vitro. Furthermore, the MeOH extract significantly inhibited M. tuberculosis growth in human macrophages. When five fractions obtained from MeOH extract were examined using the same methods, the hexane and ethyl acetate fractions showed bactericidal effects against M. tuberculosis in vitro, whereas the butanol and water fractions inhibited M. tuberculosis growth in macrophages. Because H. japonicus extract exhibited antimycobacterial activity against both free M. tuberculosis in culture medium and intracellular M. tuberculosis in human macrophages, this plant might be a good candidate for development of a new anti-tuberculosis drug.
: Recently, assessment of nitrogen balance has been required for environmental agriculture. Nutrient management using organic matters in farmlands has been strongly required as a means of extending resource-cycling agriculture and reduction of nitrogen balance. Organic matters-derived nutrients and soil-available nitrogen should be necessarily considered to manage nutrient balance in soil-plant system. In this study, we reviewed the amount of N supply according to types of organic matter such as livestock compost and green manure in arable land. In case of applied livestock compost in soil, nitrogen mineralization was influenced by nitrogen amount of livestock manure and mixed materials. And nitrogen mineralization of green manure in arable land was influenced by types of crop and return period of green manure because of change of C/N ratio. Also, nitrogen supply by organic matter in arable land can be changed by environmental factors such as temperature, moisture in soil. Therefore, nitrogen supply according to C/N ratio of organic matter and analysis method for estimation of soil nitrogen supply availability should be evaluated to set up the nutrient management model.
This research investigated the moderating effects of children's negative emotionality, activity and sociability on the relation between maternal parenting stress and children's behavior problems. Participants consisted of 1,667 preschool children from the fifth wave of the Panel Study on Korean Children. EAS was used to measure the children's temperament. Mothers reported parenting stress and children's behavior problems. The results revealed that the magnitude of association between relation between maternal parenting stress and children's behavior problems was greater for high levels of negative emotionality and activity as well as low levels of sociability. The results support a diathesis-stress model in which high negative emotionality, activity and low sociability confer vulnerability for preschool children in a high stress family.
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