We researched 3 patients diagnosed as Lateral epicondylitis (Tennis elbow). We considered it as tendinosis including irregular collagen fiber's pattern. So, acupuncture therapy and musculotendinous releasing manual therapy were used to treat the patients. We measured their pain and functional disorder by visual analogue scale (VAS), Patient-Rated Tennis Elbow Evaluation (PRTEE), and a dynamometer before and after treatment. As a result, VAS and PRTEE significantly reduced and grasping power was also improved. Therefore, we conclude that the acupuncture therapy with musculotendinous releasing manual therapy is an effective way to treat Lateral epicondylitis. But there are limits on this study due to insufficient number of cases, absence of control group and absence of follow-up after last treatment. Further studies will be needed.
Samjunghwan (SJH) was fermented using five different probiotic bacterial strains (Lactobacillus plantarum, Enterococcus faecium, Pediococcus pentosaceus, Lactobacillus acidophilus or Bifidobacterium longum) separately.We examined the inhibition of preadipocyte differentiation through Oil Red O staining and analyzed the expression of CCAAT/enhancer-binding protein α (C/EPBα), peroxisome proliferator-activated receptor γ (PPAR γ), uncoupling protein (UCP)-2, and 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase which are adipogenic transcription factors. Both Lactobacillus plantarum and Enterococcus faecium-fermented SJH reduced Oil Red O dye staining compared with the same dose of non-fermented SJH. Only Lactobacillus plantarum-fermented SJH inhibited all adipogenic transcription factors and showed the best down-regulation of PPAR γ, UCP-2, and HMG-CoA reductase compared with the same dose of non-fermented SJH. The effect of SJH on the inhibition of preadipocyte differentiation was more prominent from the fermented SJH. Lactobacillus plantarum-fermented SJH, in particular, blocks the expression of PPARγ, UCP-2, HMG-CoA reductase.
Currently, many countries have an interest in developing cosmetics materials using native plants. In this aspect, there is increasing need to develop cosmetics materials using native plants in our county. In the present study, calluses were induced from Artemisia annua Linne, which was highlighted because of its useful effects, such as anti-cancer, anti-fungal and anti-inflammation. Water and ethanol extractions were performed from the calluses of Artemisia annua Linne. After the mass production of Artemisia annua Linne's calluses, water and ethanol extraction was performed to examine its functional roles in healing wounds and inflammation. The differences in the effective elements were observed in the ethanol extract. The callus showed anti-inflammation activity through the suppression of the inflammation-related gene, COX-2, and ethanol extracts showed their ability to heal wounds. Overall, these results suggest that the extract of Artemisia annua Linne's calluses is a natural and environment-friendly material, and can be used as medical supplies associated with anti-inflammation and healing wounds.
One of the most effective ways of preventing skin aging is to protect the skin from UV radiation, which was identified as the primary cause of photoaging. Therefore, it is necessary to develop natural and environment-friendly materials to the human skin. This study examined the effects of MAAs extracted from Chlamydononas hedleyi on UV protection and anti-inflammation in human skin cells. The function of porphyra-334 in the skin, which was isolated and purified from MMAs mixture, was tested in terms of its UV protective ability and anti-inflammation. As a result, porphyra-334 played a role in protecting the skin from UV radiation and anti-inflammation through the suppression of COX-2 expression. These results suggest that porphyra-334 can be a useful material in cosmetic products because it can protect the skin from UV radiation and anti-inflammation.
S a n gHy u nMo h 1 ,S u n g-S u kS u h 2 ,Mo o nJ i nCh o 1 ,MiYo u n gS o n g 1 , J i n i kHwa n g 2 ,Mi r y eP a r k 2 a n dT a e k-Ky u nL e e 2 * 1 An t i-a g i n gRe s e a r c hI n s t i t u t eo fB I OF D&C Co. , L t d. 2 S o u t hS e aE n v i r o n me n tRe s e a r c hDe p a r t me n t ,Ko r e aI n s t i t u t eo fOc e a nS c i e n c e& T e c h n o l o g y 요 약 천연물 유래 자외선차단제 개발을 위해 미세조류 추출물 및 my c o s p o r i n e-l i k ea mi n oa c i d s(MAAs) 의 활용가능성을 연구하였다. C h l a my c o mo n a sh e d l e y i 추출물과 추출물 분획물인 MAAs 가 각각 7 % 포함된 자외선차단크림을 제조하고 인체 적용시험을 실시하였다.
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