The purpose of this study was to identify blood and body fluids exposure, and factors influencing compliance with standard precautions among nurses. Participants consisted of 144 nurses in three general hospitals located in C province. Data were collected using a questionnaire that consisted of awareness, compliance, safety environment and attitude toward standard precautions. A total of 40.3% of participants had been injured by syringes or sharp tools that had already been used for patients within the last 1 year 1.01 times. Moreover, 22.9% of participants had been exposed to blood and body fluid of patients 1.06 times within the last 1 year. The mean score for compliance with standard precautions was lower than its awareness. There was a significant correlation between compliance and awareness and a safe environment. Multiple regression revealed an adjusted R 2 of 0.166 with the awareness score serving as the major predictor variable for compliance of standard precautions. Therefore, it is necessary to develop strategies to apply to systemic and continuous education regarding standard precautions and to foster a safe environment to enhance nurses' compliance with standard precautions.
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