Recently quick-drying antiseptics including 0.5 w/v chlorhexidine gluconate/gel-alcohol (0.5 CHG GA) have been sold in Japan. In this study, hand antiseptic eŠects and side eŠects of rough skin were compared with 0.2 w/v benzalkonium chloride/liquid-alcohol (0.2BAC LA) which is the standard product. 0.5CHG GA had similar antiseptic eŠect to 0.2BAC LA immediately after hand antisepsis. 0.5CHG GA was superior to 0.2BAC LA during the 3 hours after hand antisepsis. There was no diŠerence in the side eŠects of rough skin. Therefore, 0.5CHG GA is useful compared with 0.2BAC LA for prolonged hand antisepsis eŠects.Key wordsquick-drying antiseptics, 0.5 w/v chlorhexidine gluconate/gel-alcohol, 0.2 w/v benzalkonium chloride/liquid-alcohol
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