Significance Singlemolecule detection promotes the development of biological research because it reveals details that remain concealed to ensemble measurements. However, the detection and analysis of single molecules confront great challenges. On the one hand, single molecules produce very weak signals, requiring extremely sensitive detection methods. On the other hand, the sizes of single molecules are mainly confined to the nanoscale and they move with the naturally random state. It is necessary to isolate the
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.