Obesity is considered as one important risk factor for many health problems. Salvia officinalis is proven to have benefit in cases of hypercholesterolemia, diabetes and obesity. Also, Plantago ovata is believed to have effects on many diseases that affect the body including obesity. This study aims to assess the effect of both Salvia officinalis and Plantago ovata on weight loss using obese rats with an evaluation of their effects on serum lipids, liver and kidney functions in different levels of concentration. Forty eight male albino rats weighing 1502g were divided into eight groups and administered P. ovata and S. officinalis at different levels daily for 28 days. Blood samples were taken from each rat and centrifuged at 3000 rpm for 20 minutes. Serum was separated and stored at-20 degree C until biochemical estimations were carried out then the samples were analysed for HDL. LDL. VLDL , liver enzymes and kidney functions. Results showed that HDL-c levels were significantly increased in the treatment groups, while LDL-c levels were decreased significantly as compared to control positive. Liver enzymes (ALT and AST) were significantly decreased in all treatment groups compared to control positive. Also, concerning uric acid and urea nitrogen, the levels were reduced compared to control positive. Treating obese rats with different levels of P. ovata, S. officinalis and a mixture of them caused significant improvements in the biochemical measures and the best results seems to be recorded for the mixture diet 7,5% P. ovata and S. officinalis are useful for obese patients regarding prevention of heart diseases and hardening of arteries.
This study wasaimed to investigate the effect of Ziziphus spina-Christi and Cyperusesculentusfruits on rats with Liver Disorders. Forty eight white male albino rats, weighing 140-150 g were used in this study. The animals were divided into two main groups. The first main group (n=6) was kept as a control (-ve) group, while rats in the second (n=42) were injected by Carbon Tetrachloride (CCL 4 )to induce liver disorder. One of them was kept as a control (+) group and the other six groups treated with different percentages of Christ's Thorn,Tiger Nut fruit and mixture of them(2.5% and 5%) from the basel diet. At the end of experimental period (28 days), rats were fasted over night before slaughtering and blood was collected then centrifuged to separate the serum and estimate liver functions (AST,ALT and ALP) kidney functions (urea, creatinine and uric acid) lipid profile (T.C, T.G and HDL-c) while LDL-c and VLDL-c were calculated and blood analysis (HB ,RBCs ,HCT ,WBCs and PLT). The obtained results revealed that, treated groups by CCL 4 led to significant decrease in body weight gain% , HDL , total protein , Albumin and Globulin and increased AST,ALT and ALP, cholesterol, triglycerides, LDL-c, VLDL-c, uric acid, urea, creatinine. Treating groups which fed on Christ's Thorn, tiger nut fruit and mixture of themshowed significantly (P≤ 0.05) decreased levels of AST,ALT and ALP, Ldl , Vldl , cholesterol, triglycerides , urea, creatinine and uric acidand increase Hdl , total protein , Albumin and Globulin . It could be concluded that Christ's Thornand Tiger Nut fruit were effective inprotecting against hepatic rats not only decreased the level of AST,ALT and ALP but also has beneficial effect on lipids profile and renal profile. Therefore, data recommendas tested Christ's Thornand Tiger Nut by a moderate amount to be included in our daily diets.
Obesity is considered as one important risk factor for many health problems. Salvia officinalis is proven to have benefit in cases of hypercholesterolemia, diabetes and obesity. Also, Plantago ovata is believed to have effects on many diseases that affect the body including obesity. This study aims to assess the effect of both Salvia officinalis and Plantago ovata on weight loss using obese rats with an evaluation of their effects on serum lipids, liver and kidney functions in different levels of concentration. Forty eight male albino rats weighing 1502g were divided into eight groups and administered P. ovata and S. officinalis at different levels daily for 28 days. Blood samples were taken from each rat and centrifuged at 3000 rpm for 20 minutes. Serum was separated and stored at-20 degree C until biochemical estimations were carried out then the samples were analysed for HDL. LDL. VLDL , liver enzymes and kidney functions. Results showed that HDL-c levels were significantly increased in the treatment groups, while LDL-c levels were decreased significantly as compared to control positive. Liver enzymes (ALT and AST) were significantly decreased in all treatment groups compared to control positive. Also, concerning uric acid and urea nitrogen, the levels were reduced compared to control positive. Treating obese rats with different levels of P. ovata, S. officinalis and a mixture of them caused significant improvements in the biochemical measures and the best results seems to be recorded for the mixture diet 7,5% P. ovata and S. officinalis are useful for obese patients regarding prevention of heart diseases and hardening of arteries.
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