It was noted that during 25 years of scientific and teaching activity N. F. Filatov has made a significant contribution to the development of world Pediatrics. He is the author of over 70 scientific works, including «A short textbook of pediatric diseases» (1893), that was published in 12 editions, and «Clinical lectures» (1900). His monograph «Lectures on acute infectious diseases» (1885) was published in 4 editions, «Semiotics and diagnosis of childhood diseases» (1890) – 9 editions, it istranslated into German, Czech, Italian, Hungarian and French. Many generations of pediatricians have studied on N.F. Filatov’s monographs and manuals. He described the infectious disease named Filatov scarlatinal rubella. Later it was described by the British physician Dukes; one of the presently used names of the disease is Filatov-Dukes disease. In the first edition of «Lectures on infectious diseases» N. F. Filatov described not known until that time infectious mononucleosis, which he called idiopathic inflammation of the cervical lymphatic nodes. The disease is now often called the Filatov’s disease. In 1895 N. F. Filatov, described an important diagnostic sign of measles – the appearance in the catarrhal period of illness of grayish-white lesions on the mucose membrane of lips and cheeks 1–2 days prior to the appearance of rash. As was established later, this sign was first described by A. P. Belsky in 1890, then, independently, by N.F. Filatov, and in 1896 by Koplik. In the literature, this symptom is known as Belsky-Filatov-Koplik spots. N.F. Filatov described the pathogenesis of some forms of oedema syndrome in children, published works on prolonged afebrile forms of the flu. N.F. Filatov was developing a clinical-physiological direction in Pediatrics. He created a large school of native pediatricians. Among his students were famous pediatricians V.I. Molchanov and G.N. Speransky.
The article shows that a significant proportion of neuroendocrine tumors of the pancreas are non-functional, i.e., not secreting into the blood a variety of gastrointestinal hormones and polypeptides and as a result, not accompanied by typical clinical manifestations. Unfortunately, often the scan search starts in the detection of distant metastases of neuroendocrine tumors and development of cancer cachexia. Noted that the diagnosis of neuroendocrine tumors of the pancreas is a highly complex task, the solution of which depends on the choice of treatment and its remote results. Currently, the only radical method of treatment of hormonally functioning tumors of the pancreas is surgical. It is indicated that symptomatic therapy can be considered as a stage of preoperative preparation of the patient. The indication for surgical treatment in this situation, along with the ineffectiveness of conservative treatment is the size of detectable formations of 2 cm or more, which is a risk factor of distant metastases. Stressed that according to modern views of patients with nonfunctioning neuroendocrine tumors of the pancreas are subject to surgical treatment. Given that in 70-92% of cases they are malignant, most often used distal or extensive pancreatoduodenal resection. Currently, noted that the large size of the tumors are not a contraindication to surgery and if the tumor dormant, to 1 cm, the possibility of a short observation. Any tumors found in the pancreas, needs to be taken out of the context, or if it is possible – is widely excised. The article examines the rational and integrated use of modern Arsenal of surgical and therapeutic methods, which enable significantly prolong life, improve its quality in patients with metastatic forms of neuroendocrine tumors of the pancreas.
по праву занимает лидирующее место в ряду имен выдающихся ученых, прославивших Россию. Творчество великого хирурга, мыслителя, травматолога, ортопеда, владевшего даром художествен-ного откровения, оставило след в клинической медицине. Гениальный хирург, верный последователь Н.И. Пирогова и Н.В. Склифосовского, Г.И. Турнер на протяжении почти 60 лет своей научно-практической деятельности успешно развивал мировую медицину, обогащая ее бесценным клиническим опытом. Генрих Иванович Турнер (рис. 1) родился 29 сентября 1858 г. в Петербурге в многодетной семье. Детство для Генриха закончилось в 13 лет, когда от туберкулеза умер отец, и забота о шестерых детях легла на его с матерью плечи. Вскоре осиротевшая семья перебралась жить на Херсонскую улицу. Жизнь семьи в новых условиях сложилась суровой, полной
The main milestones in the life and work of T. Kocher are presented. Illuminated little-known interesting facts from the life of a professor. T. Kocher studied the problems of asepsis and antisepsis, abdominal surgery, thyroid surgery, traumatology. He deepened his teaching of the antisepsis and asepsis, introduced the concept of Implant Infection. It is noted that Kocher has developed sterilization methods suture material. He suggested operative access to the liver and biliary tracts, an original method of gastrectomy, methods for mobilizing the duodenum, surgical treatment of inguinal hernias, which are now described in textbooks. He also developed gentle surgical approaches for the procedure on large joints (hook-shaped incisions). The reduction of shoulder dislocations according to Kocher became a part of the daily practice of surgeons and traumatologists. T. Kocher's research on the problems of diseases of the thyroid gland is world famous. T. Kocher was awarded the 1909 Nobel Prize for his work on the physiology, pathology and surgery of the thyroid gland. He proposed some surgical instruments (hemostatic clamp, grooved probe, gastric clamp, etc.), a gastric tube was put into practice. The published manual on operative surgery has survived 5 reprints (1892–1907) and has been translated into many world's languages.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.