Invasive mycoses caused by fungi of the genus Aspergillus, today remain an urgent clinical problem in oncological patients. In 10–20 % of patients with primary by aspergilloma can be detected in the Central nervous system. The article describes a case of neuroaspergillosis in an immunocompromised patient with choroid carcinoma of the right parietal-occipital lobe of the brain. Correct interpretation of risk factors, clinical symptoms and imaging techniques, early diagnosis with verification the pathological process, the use of fungistatic and fungicidal drugs allowed to avoid the negative consequences of fungal neuroinfection.
Bilateral nephroblastoma is rare and is about 5 % of the total number of patients. The modern strategy of treatment children with bilateral Wilms tumor requires a comprehensive approach. An important task is to preserve as much of the renal parenchyma as possible, which will be sufficient for normal kidney function and development of the child. However, in subtotal kidney damage organ-preserving treatment is not always possible. In this case, the only curative option is bilateral nephrectomy followed by continuous renal replacement therapy. To date, the literature describes isolated cases of adjuvant chemotherapy in children on peritoneal dialysis. The article presents a clinical case of specific therapy with topotecan for a child after bilateral nephrectomy, a carrier of peritoneal dialysis catheter on the background of progression of the underlying disease.
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