Asthenic disorders are one of the most critical and challenging issues in various medical disciplines. Postinfectious asthenia is relatively common. Its major presentations are a significant long-lasting physical and intellectual fatigue. The COVID-19 infection results in numerous emotional, cognitive, and vegetative disorders, drastically reducing the quality of life and preventing rehabilitation and returning to baseline everyday activity. The rationale for introducing the term "post-COVID syndrome" is accounted for by the high prevalence of asthenic, cognitive, and vegetative disorders after the COVID-19 infection and their higher rate compared to other infections and a significant reduction in the quality of life. This paper discusses clinical presentations of the post-COVID syndrome and analyzes the findings on the pathogenesis of this condition. The authors declare that all patients after the COVID-19 infection should undergo the assessment of cognitive functions and asthenic syndrome followed by adequate treatment prescription. The paper describes treatment modalities for the post-COVID syndrome, e.g., the perspective use of Prospecta®, which demonstrated the efficacy for acute and chronic disorders of brain circulation. KEYWORDS: COVID-19, post-COVID syndrome, asthenic disorders, cognitive disorders, Prospecta. FOR CITATION: Kamchatnov P.R., Solov’eva E.Yu., Khasanova D.R., Fateeva V.V. Asthenic and cognitive disorders after the COVID-19 infection. Russian Medical Inquiry. 2021;5(10):636–641 (in Russ.). DOI: 10.32364/2587-6821-2021-5-10-636-641.
Дорсопатия -исключительно распространенный в популяции скелетно-мышечный болевой синдром. Для лечения паци-ентов с дорсопатиями наиболее широко используются нестероидные противовоспалительные препараты. Как правило, они оказывают выраженные противоболевой и противовоспалительный эффекты, однако их использование ассоциирова-но с риском развития побочных эффектов, особенно высоким у пациентов с полиморбидностью, нуждающихся в одно-временном приеме нескольких лекарственных препаратов. Рассматривается возможность применения трансдермальной формы диклофенака (Вольтарен Эмульгель) у пациентов с дорсопатиями. Приводятся результаты исследований, посвя-щенных изучению биодоступности препарата, его эффективности и переносимости.
The efficacy and safety of divasa in asthenic and mild to moderate cognitive disorders in elderly and senile subjects were shown. There is a need for a multicenter placebo-controlled trial on the efficacy of divasa to treat cognitive and asthenic disorders in elderly patients.
Low back pain (LBP) is an extremely widespread syndrome in the population. Nonsteroidal Inflammatory drugs are most frequently used in treatment of patients with LBP. The use of these drugs causes adverse effects, the risk of which can be minimized. To decrease the risk, B-group vitamins are used in the complex treatment. The possibility of simultaneous using of artrozan (meloxicam) and cyanocobalamine (B-group vitamin complex) in the treatment of LBP is considered.
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