In recent years, researchers have mainly focused on the humoral and endogenous predictors of atherosclerosis, not paying due attention to anatomical, functional and biomechanical factors. The purpose of the study is an anatomical and functional analysis of the role of extrasystoles as a risk factor for atherosclerosis of the arterial vessels. A total of 270 patients with supraventricular and ventricular extrasystoles were examined. Among the patients there were 162 men and 108 women aged 63.4 ± 6.6 years. The patients underwent sphygmography, electrocardiography, echocardiography and Doppler ultrasound of the arterial main vessels. Anatomical and functional and biomechanical indices of the heart and vessels were determined. The results of the study showed that there are four structural and functional effects of extrasistoly, which play an important role as predictors of atherosclerosis (arterial sprain, mechanical damage to their endothelium, the appearance of additional pulsation waves and the formation of atheroma). The authors believe that the risk factor is not the extrasystole itself, but the pulse wave of the first post-extrasystolic contraction, especially after an early extrasystole, which occurred before the opening of the mitral valve, therefore the treatment tactics and the expediency of its at extrasystoles in many aspects is determined by the degree of hemodynamic disturbances in each specific variant of this rhythm disturbance.
Клиника факультетской хирургии Самарского государственного медицинского университета, Самара, Россия, 443079 Цель исследования-представить гибридную технологию хирургического лечения больных с многоуровневым поражением как пре-, так и внутричерепных артерий, кровоснабжающих вертебрально-базилярный бассейн. Материал и методы. Авторами разработан и внедрен в клиническую практику способ хирургического лечения больных с сочетанием стеноза и патологической извитости позвоночной артерии в V1 сегменте со стенозом V4 сегмента и стенозом основной артерии. Способ заключается в последовательном, за одну операцию выполнения транспозиции V1 сегмента позвоночной артерии в общую сонную артерию, стентирования V4 сегмента позвоночной артерии и стентирования основной артерии. Продемонстрированы результаты лечения 3 больных по разработанной технологии. Ключевые слова: вертебрально-базилярная недостаточность, позвоночная артерия, основная артерия, экстракраниальное, интракраниальное поражение.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.