Acne, one of the most common skin problems in dermatological practice, is a condition that affects not only adolescents but also adults. While approximately 80% of cases occurring in adulthood are persistent from teenage years, around 20% are described as ‘late-onset' disease, appearing for the first time in adulthood. The disease can be triggered by hormonal changes (including a change from one contraceptive to another), or it can be induced by certain nonhormonal medications, emotional stress, and various underlying diseases such as polycystic ovary syndrome. In many cases acne becomes a chronic skin condition with undulating activity, including improvement and relapse phases, and is often experienced as a major psychological burden. It is, therefore, even more important to provide an effective as well as a safe and tolerable treatment. The spectrum of topical acne treatments has expanded substantially in recent years and various topical medications are available, ranging from azelaic acid, antibiotics, retinoids and benzoyl peroxide to several fixed combinations of these active compounds. The following case collection illustrates how 15% azelaic acid gel, as a well-established monotherapy, can be successfully employed to treat mild-to-moderate forms of adult female acne.
A rare case study of actinic reticuloid is presented. Analysis of literature, clinical and pathomorphological criteria of I diagnostics are described.
Goal. To assess the clinical efficacy of a monotherapy with the use of products belonging to the Hyseac line for the treatment of light acne. Materials and methods. The study involved 28 patients with light acne, who were administered products belonging to the Hyseac line as a monotherapy. The dynamics of the skin processes was assessed visually (S. Liden’s acne general severity scale) and with the use of instrumental methods — sebometry (Callegari SOFT 5.5). Results. High efficacy of the administered therapy was registered in 39% of the subjects, substantial improvement was recorded in 53% of the subjects, improvement — in 8% of the subjects while no effect was registered in 0% of the subjects. Conclusion. The drug demonstrated high clinical efficacy, good tolerance and absence of any adverse effects, which makes it possible to recommend products belonging to the Hyseac line as a monotherapy and concomitant treatment of light acne.
1 ФГБоу Впо «ростовский государственный медицинский университет» Минздрава россии, ростов-на-дону, россия, 344022; 2 клиника «Мир-о-МЕд», Краснодар, россия, 350020; 3 «центр кольпоскопии и цервикальной патологии», Краснодар, россия, 350089; 4 ФГБуН «институт химической физики им. Н.Н. семенова» раН, Москва, россия, 119991 В статье описаны клинико-эпидемиологические особенности папилломавирусной инфекции и представлены результаты комплексной терапии препаратом панавир у пациенток с сочетанными вирусно-бактериальными инфекциями. Цель работы -оценить эффективность комплексной терапии препаратом панавир у пациенток с сочетанными вирусно-бактериальными инфекциями. Материал и методы. проведено клинико-лабораторное обследование 320 женщин, группу наблюдения составили 70 пациенток с диагностированной папилломавирусной инфекцией. результаты. оценивая эффективность проведенной терапии, следует отметить значительное снижение вирусной нагрузки, выраженный регресс воспалительного процесса, более высокую эффективность специфической антибактериальной терапии, нормализацию кольпоскопической картины, уменьшение площади очагов хронического цервицита и CiN i более чем у 68% пациенток, элиминация вируса папилломы человека была достигнута у 35% женщин. Выводы. использование средств иммунокорригирующей и патогенетической терапии (таких как панавир), воздействующих на возбудителя и на микроорганизм, позволяет повысить результативность терапии и существенно снизить риск жизненно опасных последствий папилломавирусной инфекции.Ключевые слова: вирус папилломы человека, папилломавирусная инфекция, инфекции, передаваемые половым путем, дисплазия, панавир. The article describes the clinical and epidemiological features of human papillomavirus infection and reports the results of the complex therapy with Panavir in patients with viral and bacterial multi-infections. Objective. The study was aimed at evaluating the effectiveness of complex therapy with Panavir in patients with viral and bacterial multi-infections. Material and methods. Clinical and laboratory study involved 320 females, the study group included 70 patients diagnosed with hpV infection. Results. When assessing the effectiveness of therapy, it should be noted that there was significant reduction of viral load, pronounced regression of the inflammatory process, higher efficacy of specific antibiotic therapy, normalization of colposcopic picture, reduced area of chronic cervicitis foci and CiN i in more than 68% of patients, as well as elimination of human papilloma virus in 35% of females. Conclusions. The use of immunocorrecting and pathogenetic therapy (such as Panavir), acting on both the pathogen and microorganism, can improve the effectiveness of therapy and substantially reduce the risk of life-threatening consequences of hpV infection Current treatment options for genital papillomavirus infection
This article presents data about the etiology, pathogenesis, clinical course and methods of treatment for a rare obligate paraneoplastic dermatosis - the Bazex syndrome. The authors share their own observations.
The coronavirus infection (COVID-2019) caused by SARS-CoV-2 continues to be studied, the virus mutates, new strains differing from the previous ones by rapid spread appear. Due to the difficult epidemiological situation around the world, the long-term course of the pandemic, doctors of various disciplines are increasingly facing its consequences. 25% of patients have various types of alopecia following infection. Suppression of some growth factors due to the collapse of the immune privilege, local and systemic inflammation, oxidative stress, tissue hypoxia, microvascular insufficiency manifested by persistent capillary spasm influence hair loss. The article presents data from the analysis, out-patient medical records of patients aged 19 to 60 years who sought advice from the Ekaterininskaya clinic network with complaints of hair loss and past history of confirmed coronavirus infection. Due to the variety of trigger factors and multifaceted pathogenetic mechanisms of influence on the hair follicle in coronavirus infection, it is more appropriate to use drugs with a complex mechanism of action for the treatment. The patients received a complex drug for the treatment of alopecia, 1 tablet three times a day for 2 months, and a peptide lotion for cutaneous use with active ingredients, which activate cellular metabolism in hair follicles, encourage the hair follicles to switch to the active growth phase. A positive result during treatment was achieved in 92% of patients. Good tolerability, absence of side effects allow us to administer the drugs we use in a range of therapeutic measures in patients with diffuse hair thinning following coronavirus infection, both in monotherapy and in combination with other drugs.
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