The three in vitro and in vivo models confirmed the similarity of the cytotoxic activities of Pacliex and Taxol. Considering the above, Pacliex could be an interesting alternative Cremophor EL-free formulation of paclitaxel.

A new self-assembled and self-healing class of metal free, recyclable, heterogeneous Brønsted acid catalysts has been developed by the protonation of aniline derivatives (tetrakis(4aminophenyl)methane, leuco-crystal violet, benzidine, and p-phenylenediamine) with aromatic sulfonic acids (tetrakis(phenyl-4-sulfonic acid)methane, and 2,6-naphthalenedisulfonic acid). As a result, five three-dimensional crystalline organic salts (F-1a, F-1b, F-1c, F-2, and F-3) were obtained, linked by hydrogen bonds and additionally stabilized by the opposite charges of the components. Frameworks F-2 and F-3 were prepared for the first time and characterized by elemental analysis, X-ray structural analysis (for F-2), thermogravimetry, SEM, and FTIR spectroscopy. The catalytic activities of crystalline organic salts F-1−3 have been explored in industrially important epoxide ring-opening and acetal formation reactions. The presence of encapsulated water inside frameworks F-1a and F-2 had an inhibitory effect on the performance of the catalysts. Xray diffraction analysis of hydrated and dehydrated samples of F-1a and F-2 indicated that water of crystallization served as a crosslinking agent, diminishing the substrate induced "breathing" affinities of the frameworks.

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The original version of this article unfortunately contained an error in one of the co-author's name. The third author's name should read as "Nikolai N. Lobanov" instead of "Nikolay N. Lobanovc". The original article was corrected.

The nine-membered azonino­indole ring in the title compound arose from a ring-expansion reaction. The title compound shows acetyl­cholinesterase and butyrylcholinesterase inhibition.