The m ethod of preparation of highly stable reproducible C60 fullerene aqueous colloid solution is described. The structural organization of C6o fullerenes in aqueous solution was studied and analyzed in detail using various techniques such as chemical analysis, U V /V IS spectroscopy, atomic force and scanning tunneling microscopy, dynamic light scattering, and zeta potential methods.

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The specific features of structural self-organization of C60 fullerene and antitumor drug cisplatin (Cis) in physiological solution (0.9% NaCl) have been investigated by means of small-angle neutron scattering, scanning electron and atomic force microscopies, as well as isothermal titration calorimetry, dynamic light scattering and UV-Vis spectroscopy. The formation of C60 + Cis complexes, has been reported, unveiling the mechanism of medico-biological synergy observed during administration of the mixture of these drugs.

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