Alopecia areata is a poliethiologic immune mediated condition, associated with lesion of the hair follicles, leading to disruption of growing cycle and subsequent hair loss. Taking into account the different age of patients and repeated recurrence despite of the therapy, as well as changes in the appearance of the individual affecting psychosocial status, patchy hair loss refers to the category of socially important disorders. The introduction of computer technologies facilitated diagnostic approaches through developing of specific criteria for the diagnosis of alopecia areata, which improved its differentiation with similar dermatological conditions. This publication intended to review and analyze of clinical cases of several dermatological disorders which remind clinics of different forms of alopecia areata. The importance of trichoscopy was shown to provide differential diagnosis in various hair-loss conditions to evaluate morphometric hair and skin characteristics.

A rare clinical case of Bureau-Barrie`re-type sporadic ulcerative-mutilating acropathy is described.

The authors describe the results of a clinical study of 90 patients suffering from different clinical forms of atopic dermatitis (AD), who received hepatotropic drugs in combination with ursodeoxycholic acid. A misbalance of cellular and humoral immunity was revealed in these patients prior to the onset of treatment. The inclusion of ursodeoxycholic acid in complex treatment of AD contributed to normalization of immunity indices and regression of skin eruptions.

Short summary and results of the own clinical observations on efficacy of developed complex method on the treatment of true acantholytic pemphigus composed of traditional immunosuppressive therapy and antiviral remedy - gancyclovir are presented. The etiology of herpesvirus infection had been discussed in the pathogenesis of the disease.