Introduction.Due to anatomical features, surgical treatment of oral cancer can lead to significant functional and esthetic defects. Main methods of reconstruction can be divided into groups of local and free flaps. There are lots of publications devoted to reconstruction of defects of oral cavity with the use of local and free flaps, but only few of them contain the comparison of these methods in the aspect of functional results.Materials and methods.A total of 58 patients with oral cancer were included in our study. All patients received surgical treatment with one-time reconstruction of defect. In 34 cases we used free radial flap and in 24 – submental local flap.Results.The use of submental flap has advantages in the intraoperative time, time of recovery, functional results, with the same locoregional control.Conclusions.We suggest submental local flap and radial free flap to be the method of choice in reconstruction of mucosa and soft tissues defects in patients with primary and recurrent oral cancer.
Introduction. Surgery at the first stage has always been the gold-standard treatment for locally advanced head cancer of almost all locations. Such patients often have significant postoperative defects that cause serious functional and aesthetic disorders. This requires simultaneous defect repair. The technique of defect repair should be chosen carefully with the consideration of its benefits and potential consequences.Objective – to evaluate the efficacy of revascularized radial flaps for defect repair after combination extensive surgical excisions of head and neck tumors.Materials and methods. This study included 67 patients with head and neck cancers of different locations who had undergone surgical tumor excision followed by defect repair using a radial flap.Results. All patients had their defects repaired using radial autologous grafts. Since this study included primarily patients with oral and oropharyngeal tumors (53 patients), we also analyzed the survival in this cohort. patients were followed-up for 2 to 7 years. fourteen patients (26.4 %) developed progressive disease during this time, including 8 individuals with recurrent primary tumor and 6 individuals with regional metastases. The mean time to nasoesophageal probe removal and restored swallowing was 12.2 days; mean length of hospital stay was 13.5 days.Conclusion. Thus, radial flap is a reliable and multifunctional material that can be used to repair complex and combination defects in patients with head and neck tumors. In some cases, it is the method of choice, since it helps to achieve satisfactory quality of life. Repair of tongue defects with radial flaps ensures good functional results.
The article presents a draft of clinical recommendations for the diagnosis and treatment of medullary thyroid cancer in adult patients, which provides a modern examination algorithm, discusses the basic principles of laboratory, instrumental diagnostics and treatment approaches.
The article presents a draft of clinical recommendations for the diagnosis and treatment of differentiated thyroid cancer in adult patients, which provides a modern examination algorithm, discusses the basic principles of laboratory, instrumental diagnostics and treatment approaches.
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