The article describes pathogenetic factors of metabolic syndrome and skin diseases that are most often associated with it, gives data on treatment of metabolic syndrome.
Objective. To describe the sonopattern of limited scleroderma (LS) in the early stages after the onset of erythema.Materials and methods. The work describes a clinical case of limited plaque scleroderma. The sonographic examination was carried out on an ultrasound scanner using a transducer with operating frequencies of 10–16–18 MHz. Material sampling for the histologic examination of the skin was performed from the area with the most pronounced inflammatory changes under sonographic control.Results. It has been found that increased echogenicity of the dermis, “blurring” of the dermis/hypodermis boundary, increased echogenicity and the “stalactite-like” pattern of subcutaneous fat occur in the frst week of the disease; normalization or a signifcant improvement of the sonopattern is noted by the end of the second week or by the beginning of the third week after the onset of erythema.Conclusion. There is a certain parallelism between the histologic and sonographic patterns, which makes it possible to adequately assess both the activity and the stage of the LS process.
Infected eczema is considered to be a widespread skin disease. Recently it has had a tendency for severe disease course, resistance to therapy and frequent relapse. This article describes clinical features of manifestations of the disease, studies microflora of patient's skin lesions, antibiotic sensitivity of these microorganisms.
Цель. Дать описание сонопаттерна ограниченной глубокой склеродермии в дебюте заболевания. Материалы и методы. Произведено сопоставление клинических, сонографических и гистологических данных пациентки с глубокой формой ограниченной склеродермии. Сонографическое исследование проводилось на ультразвуковом сканере высокого класса с применением линейного датчика с рабочими частотами 10 МГц. Забор материала для гистологического исследования осуществлялся под сонографическим контролем из участка с наиболее выраженными изменениями. Результаты. Установлено, что в дебюте глубокой формы ограниченной склеродермии отмечается утолщение и повышение эхогенности дермы над участком поражения, «размытость» границы дерма/гиподерма, повышенная эхогенность подкожно-жировой клетчатки с наличием в ней гипоэхогенной зоны с неровными («рваными») контурами (зоны лимфоидной инфильтрации) и локальным увеличением (в указанной зоне) количества доплеровских сигналов при цветовом доплеровском картировании. Заключение. В дебюте ограниченной глубокой склеродермии имеет место следующий эхопаттерн: утолщение и повышение эхогенности дермы над участком поражения, «размытость» границы дерма/гиподерма, повышенная эхогенность подкожно-жировой клетчатки с наличием в ней гипоэхогенной с неровными («рваными») контурами и увеличенным количеством доплеровских сигналов (при цветовом доплеровском картировании) зоны. Purpose. Describe the sonopattern of deep morphea at the onset of the disease. Materials. Comparison of clinical, sonographic and histological data of a patient with deep morphea was made. Sonographic examination was carried out on a high-class ultrasound scanner using a linear transducer with operating frequencies of 10 MHz. The sampling of material for histological examination was carried out under sonographic control from the area with the most pronounced changes. Results. It was found that in the onset of deep morphea there is a thickening and increased echogenicity of the dermis over the affected area, “blurring” of the dermis/hypodermis border, increased echogenicity of subcutaneous fat with the presence of a hypoechoic zone in it with uneven (“torn”) contours (zones of lymphoid infiltration) and a local increase (in the indicated area) of the number of Doppler signals in color Doppler mapping. Conclusion. In the onset of the deep morphea, the following echo pattern takes place: thickening and increased echogenicity of the dermis over the affected area, “blurring” of the epidermis/dermis border, increased echogenicity of subcutaneous fat with the presence of hypoechoic tissue in it with uneven (“torn”) contours and an increased amount of Doppler signals (with color Doppler mapping) of the zone.
The article presents up-to-date literary data on the etiopathogenesis, prevalence of lichen sclerosus, defines the clinical manifestations and classification of the disease, and considers the issues of its diagnosis and treatment. The article also describes 3 clinical cases of genital lesions in female patients with localized scleroderma. In our opinion, lichen sclerosus is one of the forms of localized scleroderma.
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