Abstarct. The aim of the present investigation was to evaluate the effects of aflatoxin B1 and Mycotox NG applied either independently or together, on blood total protein, albumin, blood glucose, total bilirubin, triglycerides, cholesterol, enzyme activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (AP), gamma-glutamyl transferase (γ GT), lactate dehydrogenase (LDH) and changes in liver morphology. At the same time, the potential of supplementation of feed with a mycosorbent (Mycotox NG) was evaluated. Experiments were carried out with 40 1-day-old Toulouse geese from mixed sexes divided into one control and three treatment groups (n=10). Groups were as followed: Group I – control (0 mg/kg AFB1 not supplemented with Mycotox NG); Group II (0.5 g/kg Mycotox NG), Group III (0.5 mg/kg AFB1) and Group IV (0.5 mg/kg AFB1 and 0.5 g/kg Mycotox NG). In this study, commercially available geese of Toulouse strain were reared from day one to forty two days in the deep litter system of management and the birds were divided into four groups. Normal feed tested free of aflatoxin (AFB1), was given to the control (Group – 1). 0.5 g/kg Mycotox was supplemented with the feed to Group 2, Aflatoxin (0.5 mg/kg feed) was supplemented with the feed to Group 3 and Mycotox Ng (0.5 g/kg feed) + 0.5 mg/kg feed AFB1 was supplemented with the feed to Group 4. The duration of the experiments was 42 days. The monitored blood chemical parameters were analysed on post treatment days 21 and 42. In birds treated only with AFB1, (group III) increased blood activities of studied enzymes. At the same time, blood total protein, albumin, cholesterol, glucose and triglycerides were reduced as compared to controls. The observed histopathological changes in the liver consisted in various extent of dystrophy (congestion, vacuolar and granular dystrophy, round cell proliferation, necrobiotic changes, hyperplasia of gallbladder epithelium). The addition of mycosorbent (Mycotox NG) to the feed of Groups IV reduced substantially the changes in blood chemistry and the severity and frequency of liver histological lesions. The addition of mycosorbent (Mycotox NG) to the feed of Groups IV reduced substantially the changes in blood chemistry and the severity and frequency of liver histological lesions.
Abstract. Contamination of poultry feeds with mycotoxins is a global problem faced by poultry industry due to increased demands and availability of poor-quality cereals. The aim of the present study was to evaluate the beneficial effects of a mycotoxin binder (Mycotox NG) on relative weights of internal organs in Pekin ducks with experimental aflatoxicosis. The birds were divided into one control and six experimental groups (n=10) as follows: group І (0 mg/kg AFB1 without Mycotox NG); group ІI (0.5 g/kg Mycotox NG); group ІІI (1.0 g/kg Mycotox NG); group IV (0.2 mg/kg AFB1); group V (0.4 mg/kg AFB1); group VI (0.2 mg/kg AFB1 + 0.5 g/kg Mycotox NG) and group VII (0.4 mg/kg AFB1 + 1.0 g/kg Mycotox NG). Trial duration was 42 days. It was established that ducks fed AFB1-contaminated feed had increased relative weights of liver, kidneys, pancreas, heart, gizzard and proventriculus compared to the control group. At the same time, the relative weights of immunocompetent organs (thymus, spleen and bursa of Fabricius) were reduced. The addition of Mycotox NG to the feed contaminated with AFB1 compensated partly the changes in relative weights of visceral organs. The results from the present study demonstrated that the tested toxin binder could be effective for reduction of toxic effects of aflatoxins in domestic ducks.
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