Today, health care as one of the priority areas for the state of development requires special attention in the transition to innovative models based on the use of advanced medical concepts and digital technologies. In this regard, for medical organizations, a strategic decision, the formation of disparate architectural solutions becomes topical. Before you begin to develop models of architectural solutions, apply digital transformations to them, it is advisable to use some reference model in the digital transformation of a medical organization, which will allow you to take into account the organization’s main business and IT requirements, restrictions and technologies used. For the formation of the reference architectural solution, a preparatory stage is needed, which allows identifying the requirements for the architecture and the corresponding restrictions. The article proposes a motivational expansion, on the basis of which the requirements and limitations for the reference model of an architectural solution in the digital transformation of a medical organization are formulated.