The analysis of the literature data on perfusion computed tomography (PCT) in lung diseases is presented. The description of the research method, the method role in the differential diagnosis of the changes nature in the lungs based on the data of the PCT is given. The issues that require further research are being clarified. It was noted that a PCT can become a method of choice in cases when the computed tomography data do not provide the answer to the question about the nature of detected changes in the lung.
The described clinical case shows the challenges in the differential diagnosis of primary diffuse large B-cell lymphoma of the lung. It has been shown that the diagnosis can be made only by a morphological examination of a biopsy specimen, and the specimen should be representative and allow for full histological and immunohistochemical testing. A correct diagnostic algorithm, an interdisciplinary approach, the use of new technologies, particularly radiation imaging methods, to reliably determine the primary localization and spread of the pathological process, biopsies for the morphological confirmation shorten the time to diagnosis. A quick diagnosis improves the treatment outcomes and affects the quality of life and life expectancy of patients.
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